Results 71 to 80 of about 132,043 (333)

A functional study of the esophagus in patients with non-cardiac chest pain and dysphagia [PDF]

open access: yes, 2015
Background/Aims: Nutcracker esophagus and non-specific motility disorders are the main causes of non-cardiac chest pain (NCCP), with gastroesophageal reflux in 60% of cases. Achalasia and diffuse esophageal spasm are the most frequent anomalies described
ALMASIO, Pier Luigi   +7 more
core   +1 more source

Normal 24-hour Ambulatory Esophageal pH Values in Koreans

open access: yesGut and Liver, 2008
Background/Aims: Twenty-four-hour ambulatory esophageal pH monitoring is considered the gold standard for diagnosing gastroesophageal reflux disease.
doaj   +1 more source

Esophageal Acid Exposure in Healthy Adults in Taiwan: Experience with pH Step-up Method by Dual-Channel pH-metry

open access: yesKaohsiung Journal of Medical Sciences, 2005
Esophageal acid exposure is common in normal subjects. The aim of this study was to investigate proximal and distal esophageal acid exposure in asymptomatic volunteers using dual-channel esophageal pH-metry with probe positioning by pH step-up.
Chih-Hsun Yi   +3 more
doaj   +1 more source

Gastroesophageal Reflux Disease: Diagnosis, Medication, Balneotherapy

open access: yesАрхивъ внутренней медицины, 2022
The article presents modern views on the problem of gastroesophageal reflux disease (GERD). Data on the prevalence and risk factors for the development of the disease are presented.
A. E. Shklyaev, V. M. Dudarev
doaj   +1 more source

Real‐Time In Vivo Monitoring of Anastomotic Intestinal Ischemia Using Implantable Resorbable Organic Sensors

open access: yesAdvanced Science, EarlyView.
Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl   +12 more
wiley   +1 more source

The newborn lamb as a new model for studying gastroesophageal reflux [PDF]

open access: yes, 2012
We aimed to determine whether the newborn lamb at term is a valid model for studying gastroesophageal reflux. Seven bottle-fed lambs, ages 2 to 3 days, underwent esophageal multichannel intraluminal impedance-pH monitoring (MII-pH). A total of 196 reflux
Avoine   +12 more
core   +2 more sources

Gastroesophageal Reflux in Neurologically Impaired Children: What Are the Risk Factors?

open access: yesGut and Liver, 2017
Background/AimsNeurologically impaired patients frequently suffer from gastrointestinal tract problems, such as gastroesophageal reflux disease (GERD).
Seung Kim, Hong Koh, Joon Soo Lee
doaj   +1 more source

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen   +12 more
wiley   +1 more source

Current Status of Translational Research on Gastroesophageal Reflux Disease

open access: yesThe Korean Journal of Gastroenterology, 2016
The prevalence of gastroesophageal reflux disease (GERD) and the incidence of some of its complications have risen strikingly over the last few decades.
In Du Jeong, Moo In Park
doaj   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

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