Results 81 to 90 of about 60,843 (278)

Utility of Esophageal Physiologic Tests in Eosinophilic Esophagitis

Inflammatory Intestinal Diseases
Background: In patients with eosinophilic esophagitis (EoE), the correlation between symptoms of esophageal dysfunction and endoscopic and histologic disease activity is generally poor and probably related to multiple causes such as esophageal remodeling
Jeanine Wakim El-Khoury, Ekaterina Safroneeva, Alain M. Schoepfer   +2 more
doaj   +1 more source

Proton pump inhibitor-responsive chronic cough without acid reflux: a case report

Journal of Medical Case Reports, 2007
Background Because 24-h esophageal pH monitoring is quite invasive, the diagnosis of gastroesophageal reflux disease (GERD)-associated cough has usually been made based merely on the clinical efficacy of treatment with proton pump inhibitor (PPI).
Nobata Kouichi, Asanoi Hidetsugu
doaj   +1 more source

A pH Sensor Scaffold for Mapping Spatiotemporal Gradients in Three Dimensional In Vitro Tumour Models [PDF]

Biosensors and Bioelectronics, 2022, 15, 114401
The detection of extracellular pH at single cell resolution is challenging and requires advanced sensibility. Sensing pH at a high spatial and temporal resolution might provide crucial information in understanding the role of pH and its fluctuations in a wide range of physio-pathological cellular processes, including cancer.
arxiv   +1 more source

Multi‐Walled Carbon Nanotube Reinforced Polyacrylamide‐Acrylic Acid Nanocomposite Hydrogels With Superior Mechanical and Tribological Performance as Focal Cartilage Substitute

Polymer Engineering &Science, EarlyView.
ABSTRACT Though mimicking cartilage's structure, hydrogels often present weak mechanical performance, which limits their use in cartilage repair. Here, nanocomposite hydrogel was synthesized by incorporating multi‐walled carbon nanotubes (CNTs) into a covalently bonded polyacrylamide/polyacrylic acid (PAAm/PAAc) hydrogel. Fourier transform infrared and
Yusuf Kanca, Rabia Özdemir, Daniele Dini, Bengi Özkahraman   +3 more
wiley   +1 more source

Current Advances in the Diagnosis and Treatment of Nonerosive Reflux Disease

Gastroenterology Research and Practice, 2013
Nonerosive reflux disease (NERD) is a distinct pattern of gastroesophageal reflux disease (GERD). It is defined as a subcategory of GERD characterized by troublesome reflux-related symptoms in the absence of esophageal mucosal erosions/breaks at ...
Chien-Lin Chen, Ping-I Hsu
doaj   +1 more source

High Resolution and High Precision Beam Profile Monitor for Particle Accelerator using linear contact image sensor [PDF]

, 2019
A compact beam-profile monitor was constructed using a linear contact image sensor attached to a plastic scintillator and tested using a 230 MeV proton beam. The results indicate that the beam distribution can be obtained in real-time, and the beam position with a precision of up to 0.03 mm.
arxiv   +1 more source

Nanomedicine Approaches for Autophagy Modulation in Cancer Therapy

Small Science, EarlyView.
Autophagy modulation holds promise for enhancing cancer treatment, yet clinical translation remains challenging. This review explores nanomedicine‐based strategies to improve autophagy‐targeting drugs, highlighting their synergy with chemotherapy, immunotherapy, phototherapy, and gene therapy. It also discusses nanoparticle design and clinical progress,
Sohaib Mahri, Rodolfo Villa, Ya‐Ping Shiau, Menghuan Tang, Kelsey Jane Racacho, Qiufang Zong, Saiful Islam Chowdhury, Tan Hua, Felipe Godinez, Andrew Birkeland, Tzu‐Yin Lin, Yuanpei Li   +11 more
wiley   +1 more source

pH sensing properties of flexible, bias-free graphene microelectrodes in complex fluids: from phosphate buffer solution to human serum [PDF]

arXiv, 2017
Advances in techniques for monitoring pH in complex fluids could have significant impact on analytical and biomedical applications ranging from water quality assessment to in vivo diagnostics. We developed flexible graphene microelectrodes (GEs) for rapid (< 5 seconds), very low power (femtowatt) detection of the pH of complex biofluids.
arxiv  

A 3D Pancreatic Cancer Model with Integrated Optical Sensors for Noninvasive Metabolism Monitoring and Drug Screening [PDF]

Advanced Healthcare Materials 2024, 2401138
A distinct feature of pancreatic ductal adenocarcinoma (PDAC) is a prominent tumor microenvironment (TME) with remarkable cellular and spatial heterogeneity that meaningfully impacts disease biology and treatment resistance. The dynamic crosstalk between cancer cells and the dense stromal compartment leads to spatially and temporally heterogeneous ...
arxiv   +1 more source

Diagnosis and Monitoring Pathways Using Non‐Invasive Tests in Patients With Alpha‐1 Antitrypsin Deficiency‐Associated Liver Disease: Results From an Expert Delphi Panel

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background and Aims The severe alpha‐1 antitrypsin deficiency (AATD) genotype Pi*ZZ increases the risk of liver disease (AATD‐LD) and lung disease. While non‐invasive tests (NITs) are widely used for fibrosis stage and monitoring of all liver diseases, the consensus for use in AATD‐LD is limited.
Virginia C. Clark, Mark A. Price, Jon Russo, Rohit Loomba, Alice M. Turner, Pavel Strnad   +5 more
wiley   +1 more source