Results 101 to 110 of about 4,384,248 (335)

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source

The failing heart under stress: echocardiography is an essential monitoring tool in the Intensive Care Unit [PDF]

, 2006
A
Poelaert, Jan
core   +2 more sources

Biomechanics‐Driven 3D Architecture Inference from Histology Using CellSqueeze3D

Advanced Science, EarlyView.
CellSqueeze3D reconstructs 3D cellular architecture from standard 2D histology images using biomechanical constraints and optimization. Validated on clinical datasets, it enables accurate tissue phenotyping, predicts gene mutations, and reveals significant correlations between nuclear‐cytoplasmic ratio entropy and tumor progression.
Yan Kong, Hui Lu
wiley   +1 more source

NORMATIVE VALUES FOR A NEW WATER-PERFUSED HIGH RESOLUTION MANOMETRY SYSTEM

Arquivos de Gastroenterologia, 2018
BACKGROUND: Esophageal manometry is the most reliable method to evaluate esophageal motility. High resolution manometry (HRM) provides topographic contour colored plots (Clouse Plots) with simultaneous analysis from the pharynx to the stomach.
Rogério Mariotto Bitetti da SILVA, Fernando A M HERBELLA, Daniel GUALBERTO   +2 more
doaj   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Utility of High‐Resolution Esophageal Manometry in the Evaluation of Presumed Oropharyngeal Dysphagia

OTO Open
Objective Evaluate the utility of high‐resolution esophageal manometry (HREM) in patients with symptoms of oropharyngeal dysphagia (OD) but unremarkable Modified Barium Swallow Studies (MBSS). Study Design Retrospective cohort study.
David Ahmadian, Phil Tseng, Avin Aggarwal, Austin Lever, Kathleen Cazzato, Helena Yip   +5 more
doaj   +1 more source

Estimation of Respiratory Effort Through Diaphragmatic Electromyography Features

Sensors
Respiratory effort is a critical parameter for assessing respiratory function in various pathological conditions such as obstructive sleep apnea (OSA), as well as in patients undergoing respiratory ventilation.
Gabriela Grońska, Elisabetta Peri, Xi Long, Sebastiaan Overeem, Johannes van Dijk, Massimo Mischi   +5 more
doaj   +1 more source

Esophageal motility disorders in systemic sclerosis

PAMJ Clinical Medicine, 2020
Systemic sclerosis is an autoimmune disease characterized by vasculopathy and tissue fibrosis. Esophageal disorders are often associated. The diagnosis is confirmed and characterized by high-resolution esophageal manometry (HRM).
Sara Ghani, Ilham Serraj, Mouna Salihoun, Mohamed Acharki, Nawal Kabbaj   +4 more
doaj   +1 more source

What every ICU clinician needs to know about the cardiovascular effects caused by abdominal hypertension [PDF]

, 2015
The effects of increased intra-abdominal pressure (IAP) on cardiovascular function are well recognized and include a combined negative effect on preload, afterload and contractility.
De Keulenaer, Bart L, De Waele, Jan, Malbrain, Manu LNG   +2 more
core   +1 more source

Intelligent Soft Opto‐Magnetic Robot for Minimally Invasive Interventional Therapy

Advanced Science, EarlyView.
An intelligent soft opto‐magnetic (iSOM) robot is developed that integrates remote magnetic actuation, skin‐mimic tactile perception, and photothermal ablation in a near‐millimeter‐scale design. It enables precise intraluminal navigation and localized ablation while providing real‐time optical feedback to support safe and accurate minimally invasive ...
Jingjing Guo, Xiaoyan Guo, Jian Wei, Miaowen Jiang, Qifa Su, Xian Xia, Zhuozhou Li, Rong Cai, Jianguo Ma, Bo Fu, Ming Li, Jing Zhong, Lijun Xu, Xunming Ji   +13 more
wiley   +1 more source