Results 231 to 240 of about 4,384,248 (335)

Decreased Severity of Oral Immunotherapy Induced Gastrointestinal Eosinophilic Reactions Following Revisions in Milk‐Treatment Protocol

Allergy, EarlyView.
A revised milk OIT protocol with lower daily allergen load and slower dose escalation reduced the severity and delayed onset of OIT‐induced gastrointestinal eosinophilic reactions (OITIGER). Elevated baseline absolute eosinophil count (AEC > 600/μL) was a consistent independent risk factor for OITIGER, while older age was protective.
Na'ama Epstein‐Rigbi, Matan Elkan, Yair Tzarfati, Michael B. Levy, Liat Nachshon, Yael Koren, Yitzhak Katz, Arnon Elizur, Michael R. Goldberg   +8 more
wiley   +1 more source

A Systematic Review and Meta‐Analysis on the Induction of Confirmed Eosinophilic Esophagitis as a Side Effect of Allergen Immunotherapy: An EAACI Task Force Report

Allergy, EarlyView.
ABSTRACT The European Academy of Allergy and Clinical Immunology (EAACI) established a Task Force to assess the existing data on the relationship between eosinophilic esophagitis (EoE) and allergen immunotherapy (AIT). This systematic review and meta‐analysis aimed to study the incidence of confirmed EoE, developing as a side effect of AIT to food or ...
Carlo Maria Rossi, Ingrid Terreehorst, Evaggelia Apostolidou, Martina Votto, Arzu Bakirtas, Antonella Cianferroni, George N. Konstantinou, Katerina Pantavou, Dario Antolin‐Amerigo, Enrico Heffler, Alberto Alvarez‐Perea, Montserrat Fernandez‐Rivas, Georgios K. Nikolopoulos, Oliver Pfaar, Constantinos Pitsios   +14 more
wiley   +1 more source

The Efficacy and Medium‐Term Patient‐Reported Outcomes Following Conversion From Sleeve Gastrectomy and Gastric Band to One Anastomoses Gastric Bypass: A Cohort Study

ANZ Journal of Surgery, EarlyView.
In this large single‐centre series, conversional one‐anastomosis gastric bypass was demonstrated to be safe and to deliver meaningful medium‐term weight loss with low morbidity after primary sleeve gastrectomy or gastric banding. While reflux was not universally resolved, patient‐reported satisfaction was high, and secondary enteroenterostomy provided ...
Aaron Lerch, Mokshitha Katneni, Ian Martin   +2 more
wiley   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Transient Gastric Pressure Elevation Synergizing With Impaired Esophagogastric Junction Barrier Function Plays a Pivotal Role in the Refractory Gastroesophageal Reflux Disease. [PDF]

J Neurogastroenterol Motil
Huang X, Chen Y, Ji X, Zhu L, Li T, Xia Z, Xu Z, Ge Y, Wang K, Duan L.   +9 more
europepmc   +1 more source

Paradigm Shifts in Surgery: Implications for Surgical Practice, Education, and Professional Identity

World Journal of Surgery, EarlyView.
Hanoch Kashtan, Idan Carmeli, Yeal Feferman, Ran Orgad, Daniel Solomon   +4 more
wiley   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Guidance for Liver Rehabilitation in Chronic Liver Disease

Hepatology Research, EarlyView.
ABSTRACT In April 2023, the Japan Society of Hepatology published its official guidelines on liver rehabilitation for chronic liver disease. In this article, we summarize the current evidence on the role of liver rehabilitation in slowing the progression of chronic liver disease, particularly metabolic dysfunction‐associated steatotic liver disease ...
Shuji Terai, Hiroteru Kamimura, Yoichi Hiasa, Norio Akuta, Toru Ishikawa, Yuichiro Eguchi, Hironao Okubo, Takumi Kawaguchi, Miwa Kawanaka, Tatsuo Kanda, Masaaki Korenaga, Ryotaro Sakamori, Masahito Shimizu, Yoshio Sumida, Ryosuke Tateishi, Atsushi Tanaka, Naoki Tanaka, Yasuo Tanaka, Yuki Tahata, Masato Nakai, Tadashi Namisaki, Takashi Nishimura, Atsushi Hiraoka, Takeshi Matsui, Nami Mori, Akio Moriya, Tetsuo Takehara   +26 more
wiley   +1 more source

A Novel Intra-Operative Irrigation-Drainage System for Robot-Assisted Thoracoscopic Esophagogastric Layered Anastomosis: Preliminary Practice and Short-Term Clinical Outcomes. [PDF]

Thorac Cancer
Zhong C, Li L, Wang Z, A-Lai GH, Zhao YS, Lin YD.   +5 more
europepmc   +1 more source