Results 61 to 70 of about 2,578,060 (251)

Comfortable sleep monitoring: using physiological process interconnectedness during sleep for novel software sensors

Frontiers in Network Physiology
IntroductionMonitoring sleep-disordered breathing typically requires many sensors, including pneumoflow masks, measuring nasal and oral airflow, and esophageal pressure catheters.
Anna Bavarsad, Anna Bavarsad, Elias August, Elias August, Erna Sif Arnardóttir, Erna Sif Arnardóttir   +5 more
doaj   +1 more source

Inhibitory Effect of Nasal Intermittent Positive Pressure Ventilation on Gastroesophageal Reflux. [PDF]

PLoS ONE, 2016
Non-invasive intermittent positive pressure ventilation can lead to esophageal insufflations and in turn to gastric distension. The fact that the latter induces transient relaxation of the lower esophageal sphincter implies that it may increase ...
Danny Cantin, Djamal Djeddi, Vincent Carrière, Nathalie Samson, Stéphanie Nault, Wan Lu Jia, Jennifer Beck, Jean-Paul Praud   +7 more
doaj   +1 more source

The etiology of esophageal cancer in high- and low- risk areas of Jiangsu province, China [PDF]

, 2011
[Background]Esophageal cancer (EC) remains one of the most common and fatal malignancies worldwide. The geographic variation in EC occurrence is striking, and China is an area with one of the highest incidences of EC.
Wu, M.
core  

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis

Hepatology, EarlyView., 2022
Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres, Cristina Ortiz, Nadine Bachtler, Wenyi Gu, Leon D. Grünewald, Nico Kraus, Robert Schierwagen, Christoph Hieber, Caroline Meier, Olaf Tyc, Maximilian Joseph Brol, Frank Erhard Uschner, Bart Nijmeijer, Christoph Welsch, Marie‐Luise Berres, Carmen Garcia‐Ruiz, Jose Carlos Fernandez‐Checa, Christian Trautwein, Thomas J. Vogl, Stefan Zeuzem, Jonel Trebicka, Sabine Klein   +21 more
wiley   +1 more source

Estimation of Respiratory Effort Through Diaphragmatic Electromyography Features

Sensors
Respiratory effort is a critical parameter for assessing respiratory function in various pathological conditions such as obstructive sleep apnea (OSA), as well as in patients undergoing respiratory ventilation.
Gabriela Grońska, Elisabetta Peri, Xi Long, Sebastiaan Overeem, Johannes van Dijk, Massimo Mischi   +5 more
doaj   +1 more source

Characterization of esophageal physiology using mechanical state analysis

Frontiers in Systems Neuroscience, 2016
The esophagus functions to transport swallowed fluids and food from the pharynx to the stomach. The esophageal muscles governing bolus transport comprise circular striated muscle of the proximal esophagus and circular smooth muscle of the distal ...
Richard Eduard Leibbrandt, Philip eDinning, Philip eDinning, Philip eDinning, Marcello eCosta, Charles eCock, Lukasz eWiklendt, Guangsong eWang, Jan eTack, Jan eTack, Dirk evan Beckevoort, Nathalie eRommel, Nathalie eRommel, Nathalie eRommel, Taher eOmari, Taher eOmari   +15 more
doaj   +1 more source

Pulse pressure analysis: to make a long story short. [PDF]

, 2010
Pulse pressure analysis algorithms are commonly used to measure cardiac output and to allow for the rational titration of therapy in critically ill patients. The ability of these algorithms to accurately track changes in stroke volume (and cardiac output)
Maurizio Cecconi, Rhodes, A, Andrew Rhodes, Cecconi, M   +3 more
core   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

O‐GlcNAcylation Regulation of SNAP29‐Dependent Autophagy Activation Dictates Chemoresistance in Gastric Cancer

Advanced Science, EarlyView.
Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.
Liang Tang, Shaoji Zhao, Ziling Shao, Tao Luo, Baifu Peng, Yifan Liu, Jinning Ye, Jianjun Peng, Kaiyu Sun, Jianbo Xu   +9 more
wiley   +1 more source