Three-Dimensional Myoarchitecture of the Lower Esophageal Sphincter and Esophageal Hiatus Using Optical Sectioning Microscopy [PDF]
Scientific Reports, 2017 Studies to date have failed to reveal the anatomical counterpart of the lower esophageal sphincter (LES). We assessed the LES and esophageal hiatus morphology using a block containing the human LES and crural diaphragm, serially sectioned at 50 μm ...
A. Zifan +3 more
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Ambulatory high‐resolution manometry, lower esophageal sphincter lift and transient lower esophageal sphincter relaxation [PDF]
Neurogastroenterology & Motility, 2011 AbstractBackground Lower esophageal sphincter (LES) lift seen on high‐resolution manometry (HRM) is a possible surrogate marker of the longitudinal muscle contraction of the esophagus. Recent studies suggest that longitudinal muscle contraction of the esophagus induces LES relaxation.Aim Our goal was to determine: (i) the feasibility of prolonged ...
R K, Mittal +4 more
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The Effects of Chronic Opioid Therapy on Achalasia and the Upper Esophageal Sphincter [PDF]
Medical SciencesBackground: The rise of opioid drug usage in the U.S. correlates with increasing recognition of gastrointestinal side effects, especially in the esophagus. The literature has recently noted that abnormalities in the upper esophageal sphincter (UES) are a
Joshua Kalapala +7 more
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Physiological Determinants of Lower Esophageal Sphincter Function
Gastroenterology, 1971 The factors which determine lower esophageal sphincter (LES) function in man are poorly understood. The purpose of this study is to define and compare the physiological characteristics of LES circular smooth muscle to smooth muscle from the adjacent esophagus and stomach of the opossum in vitro as a basis for understanding LES function in vivo.
W, Lipshutz, S, Cohen
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High-resolution esophageal manometry in patients with achalasia
Вестник хирургии имени И.И. Грекова, 2021 Introduction. At present, high-resolution esophageal manometry is the «gold standard» for the diagnosis of esophageal achalasia, based on the determination of the integrated relaxation pressure of the lower esophageal sphincter, the value of which in the
A. A. Smirnov +4 more
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Science Advances, 2023 Electrical stimulation is a promising method to modulate gastrointestinal disorders. However, conventional stimulators need invasive implantation and removal surgeries associated with risks of infection and secondary injuries.
Chong Zhang +16 more
semanticscholar +1 more source
Peroral endoscopic myotomy can improve esophageal motility in patients with achalasia from a large sample self-control research (66 patients). [PDF]
PLoS ONE, 2015 Peroral endoscopic myotomy (POEM) as a new approach to achalasia attracts broad attention. The primary objective of this study was to evaluate the results with esophageal motility after POEM through the first large sample clinical research.We have a self-
Shuangzhe Yao, Enqiang Linghu
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Pharmacological Treatments of Esophageal Dysphagia
The Korean Journal of Gastroenterology, 2021 Patients with esophageal dysphagia need a step-by-step approach for diagnosis and treatment. Endoscopic with biopsy and barium esophagogram are the essential tests evaluating anatomical abnormality and esophageal bolus stasis.
Yu Kyung Cho
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A mechanics-based perspective on the pressure-cross-sectional area loop within the esophageal body
Frontiers in Physiology, 2023 Introduction: Plotting the pressure-cross-sectional area (P-CSA) hysteresis loops within the esophagus during a contraction cycle can provide mechanistic insights into esophageal motor function.
Guy Elisha +6 more
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Diagnostic Approach for Esophagogastric Junction Outflow Obstruction
The Korean Journal of Gastroenterology, 2020 Esophageal manometry is the gold standard test for diagnosing primary esophageal motility disorder. With the various metrics of the high-resolution esophageal manometry, the Chicago classification provides a standard approach for the manometric diagnosis
Yu Kyung Cho
doaj +1 more source