Results 181 to 190 of about 65,121 (240)

Clinical features and long‐term outcomes of lower esophageal sphincter‐dependent and lower esophageal sphincter‐independent jackhammer esophagus

Neurogastroenterology and Motility, 2018
The most recent Chicago Classification expanded the criteria for diagnosis of jackhammer esophagus (JHE) to include the distal contractile integral (DCI) of the lower esophageal sphincter (LES).
A. Kahn, Mohanad T. Al-Qaisi, Robert A. Obeid, D. Katzka, K. Ravi, F. Ramirez, M. Crowell, M. Vela   +7 more
semanticscholar   +1 more source

Lower Esophageal Sphincter in Reflux Esophagitis

Scandinavian Journal of Gastroenterology, 1976
Lower esophageal sphincter pressure (LESP) was studied by intraluminal perfusion-manometry in the resting state and after graded intravenous doses of pentagastrin in 12 healthy subjects and 27 patients with reflux esophagitis. These patients were classified as having ulcerative (11) or non-ulcerative esophagitis (16) by histological examination and ...
U, Scheurer, F, Halter
openaire   +2 more sources

The hypertensive lower esophageal sphincter

The American Journal of Surgery, 1996
This study defines the entity of the hypertensive lower esophageal sphincter (HLES) and its treatment, including surgical implications.Esophageal manometry was performed on 1,300 patients. Of these, 53 (4%) had HLES with resting pressure > 26.5 mm Hg, defined as the upper limit of normal resting LES pressure.
N, Katada, R A, Hinder, P R, Hinder, R J, Lund, G, Perdikis, R A, Stalzer, T R, McGinn   +6 more
openaire   +2 more sources

Lower Esophageal Sphincter Pressure as an Index of Lower Esophageal Sphincter Strength

Gastroenterology, 1970
The ability of pressures measured in the lower esophageal sphincter to assess accurately the strength of the sphincter cannot be evaluated without a suitable objective measurement of sphincter strength. This study describes a measurement of strength and compares it with sphincter pressure.
S, Cohen, L D, Harris
openaire   +2 more sources

Lower esophageal sphincter pressure in histologic esophagitis

Digestive Diseases and Sciences, 1980
The fasting lower esophageal sphincter pressure of 18 normal volunteers was compared to 22 patients with symptoms and objective evidence of gastroesophageal reflux. Lower esophageal sphincter pressure was measured by rapid pull-through using an 8-lumen radially perfused catheter that sampled pressure every45 degrees around the circumference of the ...
R W, Welch, K, Luckmann, P, Ricks, S T, Drake, G, Bannayan, L, Owensby   +5 more
openaire   +2 more sources

Disorders of the Lower Esophageal Sphincter

Annual Review of Medicine, 1975
The junction of the esophagus and stomach in man is marked by a zone of elevated pressure which has been called the lower esophageal sphincter (LES) (1, 2). The purpose of this sphincter mechanism is to prevent regurgitation of gastric contents from a positive pressure cavity into the esophagus which maintains a pressure negative to the atmosphere (3 ...
R S, Fisher, S, Cohen
openaire   +2 more sources

Lower Esophageal Sphincter Dysfunction in Achalasia

Gastroenterology, 1971
In patients with achalasia, lower esophageal sphincter (LES) dysfunction plays an important role in the impairment of esophageal emptying. To evaluate this dysfunction, the manometric characteristics of the LES were recorded for 20 normals and for 16 patients with achalasia, both before and after pneumatic dilation.
S, Cohen, W, Lipshutz
openaire   +2 more sources

Pathogenesis of Lower-Esophageal-Sphincter Incompetence

New England Journal of Medicine, 1973
Abstract Since patients with symptomatic gastroesophageal reflux have diminished lower-esophagealsphincter pressure, we studied the pathogenesis of this diminished sphincteric pressure. In 23 patients with symptomatic reflux as compared to 20 controls, the lower-esophageal-sphincter response to direct muscle stimulation by a parasympathomimetic drug ...
W H, Lipshutz, R D, Gaskins, W M, Lukash, J, Sode   +3 more
openaire   +2 more sources

The Lower Esophageal Sphincter

2014
The lower esophageal sphincter (LES) is a complex area of circular muscle on the distal esophagus and proximal stomach several centimeters in length. Together with the diaphragmatic crura and the structure of the angle of His, the LES makes up the backbone of the gastroesophageal reflux barrier.
Christina L. Greene, Steven R. DeMeester
openaire   +1 more source

The Lower Esophageal Sphincter

Annals of Internal Medicine, 1975
Current concepts in physiology and pathophysiology of lower esophageal sphincteric mechanism are reviewed. With recent advances in manometric method for more accurate in-vivo human studies combined with in-vivo and in-vitro studies in animal models, there is much information regarding function of this sphincter.
openaire   +2 more sources