Results 81 to 90 of about 95,729 (244)

Proton pump inhibitors: are they overutilised in clinical practice and do they pose significant risk? [PDF]

open access: yes, 2012
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/92027/1/j.1742-1241.2012.02921.x ...
American Society of Health-System Pharmacists   +68 more
core   +1 more source

Combined Lyon and Milan Scores Predict Gerd Management Outcome Better Than Either Score Alone or Their Individual Components

open access: yesAlimentary Pharmacology &Therapeutics, Volume 62, Issue 7, Page 710-721, October 2025.
The Lyon and Milan scores outperformed AET and DeMeester score in predicting outcomes in GERD patients. When concordant, they provide optimal predictive accuracy, guiding escalation of therapy. ABSTRACT Background Confidence in gastro‐oesophageal reflux disease (GERD) diagnosis is crucial to improve outcomes from escalation of treatment. The Lyon score
Stefano Siboni   +27 more
wiley   +1 more source

A Review of the Management of Gastric Acid-Related Diseases: Focus on Rabeprazole

open access: yesClinical Medicine Insights: Gastroenterology, 2011
Current treatment guidelines for acid-related diseases (ARDs) recommend first-line treatment with a proton pump inhibitor (PPI) to reduce gastric acid production. PPIs are indicated in the management of gastroesophageal reflux disease (reflux esophagitis,
Motoyasu Kusano   +7 more
doaj   +1 more source

Epidemiology of Peptic Ulcer Disease: Endoscopic Results of a Systematic Investigation in Iran [PDF]

open access: yes
BACKGROUND Peptic ulcer disease is a multifactorial health problem affecting almost all populations worldwide. Large scale population-based studies are crucial to understanding its scope and specifications in various nations.
برازنده, فرهاد   +5 more
core  

Insights into the clinical, platelet and genetic landscape of inherited thrombocytopenia with malignancy risk

open access: yesBritish Journal of Haematology, Volume 207, Issue 4, Page 1565-1577, October 2025.
Inherited thrombocytopenia (IT) caused by germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk of developing haematological malignancy. This study examined the clinical, platelet and molecular characteristics of 66 patients with these conditions, who carried 24 distinct genetic variants in the corresponding genes.
Ana Marín‐Quílez   +34 more
wiley   +1 more source

Pharmacotherapy of Peptic Ulcer Disease

open access: yesCanadian Journal of Gastroenterology, 1991
The etiology of peptic ulcer is multifactorial; except for omeprazole, all drugs used for the treatment of peptic ulcer result in healing with no statistical difference at four weeks. The healing rare increases with time for active medication and placebo,
F Molina, MM Vohra, CN Williams
doaj   +1 more source

Upper gastrointestinal alterations in kidney transplant candidates

open access: yesBrazilian Journal of Nephrology, 2018
Introduction: The incidence of gastrointestinal disorders among patients with chronic kidney disease (CKD) is high, despite the lack of a good correlation between endoscopic findings and symptoms.
João Pedro Homse Netto   +6 more
doaj   +1 more source

Prospective Study of Upper Gastro Intestinal Tract Endoscopy Finding and its Relation to Smoking in Baquba Teaching Hospital

open access: yesDiyala Journal of Medicine, 2019
Background: The associations of smoking with endoscopic finding abnormalities were established especially in peptic ulcer that found of clear relation between smoking and peptic ulcer.
Shukr Mahmood Yaseen   +1 more
doaj   +2 more sources

Columbianadin ameliorates experimental acute reflux esophagitis in rats via suppression of NF-κB pathway

open access: yesActa Cirúrgica Brasileira
Purpose: Reflux esophagitis is a condition characterized by inflammation and irritation of the esophagus, resulting from the backflow of stomach acid and other gastric contents into the esophagus. Columbianadin is a coumarin derivative that exhibits anti-
Ying Wu   +2 more
doaj   +1 more source

ESOPHAGEAL PEPTIC STENOSIS: MANAGEMENT OF A COMPLEX CASE

open access: yesJournal of the Siena Academy of Sciences, 2009
Introduction: esophageal stenosis is one of the most serious problems in patients with peptic esophagitis. It may require esophageal resection and replacement, if no other treatment is effective. Patients and methods: we report a successfully managed case of persistent esophageal stricture.
Fanti F   +5 more
openaire   +4 more sources

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