Results 131 to 140 of about 43,423 (294)
Dabigatran‐induced esophagitis with full circumferential blue pigmentation
DEN OpenDabigatran is a useful and widely used drug for stroke prevention in patients with atrial fibrillation. However, it has been reported to cause esophagitis.
Tomonori Araki +7 more
doaj +1 more source
ANZ Journal of Surgery, EarlyView.ABSTRACT Background The symptomatology of large hiatus hernia (LHH) has been historically poorly understood, with cardiorespiratory symptoms caused by LHH being underappreciated by clinicians. This study reports on the mechanisms of dyspnoea in LHH through a historical review of symptoms and evolved physiological literature, discussing likely causation.
Arunan Mahendravarman +2 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.Among 211 prospectively followed Swiss patients with eosinophilic oesophagitis, chronic rhinosinusitis was two‐ to three‐fold more common than in the general population. It was associated with greater oesophageal symptom severity and, in a quarter of cases, was experienced by patients as more debilitating than the underlying oesophageal disease ...
Gebhardt Aidan +52 more
wiley +1 more source
The Relationship between Erosive Esophagitis and Sleep Issues in Working-Aged Koreans
Gut and LiverBackground/Aims : Studies have demonstrated that gastroesophageal reflux disease has an unfavorable effect on sleep. However, it is largely unknown whether erosive esophagitis (EE) is associated with sleep issues.
Sung Keun Park +4 more
doaj +1 more source
Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
British Journal of Pharmacology, EarlyView.Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
Emerging Paediatric Uses of Dupilumab Beyond Approvals
Clinical &Experimental Allergy, EarlyView.Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese +11 more
wiley +1 more source
Journal of Gastroenterology and Hepatology, EarlyView.Esophageal distensibility and compliance provide physiologic information beyond luminal diameter alone in pediatric esophageal disease. This review proposes a practical biomechanics‐informed framework integrating FLIP assessment into interpretation of dysphagia, esophageal remodeling, dilation response, and therapeutic decision‐making in children ...
Brett J. Hoskins +2 more
wiley +1 more source
Journal of the American Geriatrics Society, EarlyView.ABSTRACT Background Restrictive transfusion (Hb < 7 g/dL) is recommended for most perioperative patients, but the optimal threshold for those with cardiovascular disease or Hb 7–10 g/dL remains uncertain. The Perioperative Transfusion Trigger Score (POTTS), which integrates adrenaline requirement, FiO2, temperature, and angina history, may standardize ...
Shucong Liang +9 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend LIGHT is a mutual mediator of intestinal and oesophageal fibroblast inflammation with common as well as tissue‐specific effects. Hydroxylase inhibitors can selectively suppress inflammatory factors in both cell types, albeit targeting different signalling pathways.
Cian M. Ohlendieck +13 more
wiley +1 more source