Results 191 to 200 of about 42,433 (281)

A SURGICAL CASE OF REFLUX ESOPHAGITIS COMPLICATED WITH ESOPHAGEAL STRICTURE AFTER OPERATION FOR PERFORATIVE PERITONITIS INDUCED BY DUODENAL ULCER

open access: bronze, 1994
Hiroshi Aoki   +11 more
openalex   +2 more sources

Super Subtotal Gastrectomy: A Novel Reconstruction Concept for Upper Gastric Cancer That Preserves the Fornix

open access: yesAnnals of Gastroenterological Surgery, Volume 9, Issue 4, Page 870-875, July 2025.
We developed a novel super subtotal gastrectomy (SSTG) technique for upper‐third gastric cancer near the esophagogastric junction. This method preserves the gastric fornix, a major site of ghrelin secretion, while maintaining an oral margin beyond the esophageal junction. SSTG offers a potential solution for reducing postoperative complications such as
Kohei Fujita   +4 more
wiley   +1 more source

Research progress of radiation esophagitis: A narrative review. [PDF]

open access: yesMedicine (Baltimore)
Wu Q   +8 more
europepmc   +1 more source

First‐in‐Human Phase 1 Study to Evaluate the Clinical Pharmacology Properties of RBN‐3143, a Novel Inhibitor of Mono‐Adenosine Diphosphate Ribosyltransferase‐PARP14

open access: yesClinical Pharmacology in Drug Development, Volume 14, Issue 7, Page 493-504, July 2025.
Abstract RBN‐3143 is an inhibitor of PARP14 in development for inflammatory diseases. Multiple assessments were conducted to evaluate the clinical pharmacology properties of RBN‐3134. A randomized, double‐blind, placebo‐controlled study assigned healthy volunteers (HVs) to single ascending doses (SADs) (25‐1000 mg) or multiple ascending doses (MADs ...
Thomas M. Polasek   +9 more
wiley   +1 more source

Indication‐Specific Dosing and Dose‐Evaluation Strategies in New Indications for Non‐Oncology Monoclonal Antibodies

open access: yesThe Journal of Clinical Pharmacology, Volume 65, Issue 7, Page 895-908, July 2025.
Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley   +1 more source

Analysis of multichannel intraluminal impedance and pH monitoring values in children with cerebral palsy: A comparative multicenter study

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 81, Issue 1, Page 125-130, July 2025.
Abstract Objectives To compare the features of multichannel intraluminal impedance and pH monitoring (MII‐pH) tracings in children with cerebral palsy (CP) and children without CP. Methods Multicenter, retrospective, analytical study. We examined tracings of children aged 1 to 15 years old, evaluated from May 2017 to January 2024.
Cristina Lorenzo   +22 more
wiley   +1 more source

A longitudinal analysis of pathogen shedding patterns in confiscated eastern box turtles

open access: yesThe Journal of Wildlife Management, Volume 89, Issue 5, July 2025.
Seventeen confiscated eastern box turtles were sampled for 4 pathogens monthly for a year to determine optimal sampling strategies and variation in pathogen shedding patterns. Observed prevalence values were within 10% of unbiased prevalence values, but the probability of detecting pathogens in an infected turtle during a given month was generally low,
Maris J. Daleo   +9 more
wiley   +1 more source

Validation of ICD‐10 Diagnosis Codes for Identification of Acute Myocardial Infarction From a US Integrated Healthcare System

open access: yesPharmacoepidemiology and Drug Safety, Volume 34, Issue 7, July 2025.
ABSTRACT Purpose Contemporary epidemiologic research on acute myocardial infarction (AMI) using electronic health records (EHR) relies on International Classification of Diseases, 10th Revision, Clinical Modification (ICD‐10‐CM) codes, but limited studies have been conducted to validate these codes in the United States.
Jeff Slezak   +10 more
wiley   +1 more source

Research Communication: Real‐World Effectiveness of Budesonide Orodispersible Tablets for Eosinophilic Oesophagitis: The Importance of Patience and Education

open access: yesAlimentary Pharmacology &Therapeutics, Volume 62, Issue 2, Page 204-207, July 2025.
Budesonide orodispersible tablets demonstrated lower rates of clinicopathological remission in this real‐world study of 94 patients compared with clinical trials. Patient education and duration of treatment (≥ 6 months) improved outcomes. ABSTRACT Budesonide orodispersible tablets (BOT) have been shown to be efficacious for eosinophilic oesophagitis ...
Sarah Taylor   +15 more
wiley   +1 more source

Cag A positivity may be protective against more severe grades of esophagitis

open access: bronze, 1998
JJ Vicari   +5 more
openalex   +1 more source

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