Results 41 to 50 of about 60,263 (313)

Esophagitis and Pneumonitis Related to Concurrent Chemoradiation ± Durvalumab Consolidation in Unresectable Stage III Non-Small-Cell Lung Cancer: Risk Assessment and Management Recommendations Based on a Modified Delphi Process

open access: yesCurrent Oncology
The addition of durvalumab consolidation to concurrent chemoradiation therapy (cCRT) has fundamentally changed the standard of care for patients with unresectable stage III non-small-cell lung cancer (NSCLC). Nevertheless, concerns related to esophagitis
Anthony M. Brade   +8 more
doaj   +1 more source

Invasive Candida pneumonia, in association with Candida esophagitis and gastritis, in a presumably immunocompetent patient

open access: yesAutopsy and Case Reports, 2023
Candida pneumonia remains a difficult diagnosis and is most common in immunocompromised individuals. It has been rarely reported in immunocompetent individuals.
Devon Jackson   +3 more
doaj  

Association Between Esophagitis Severity and GERDQ Score, Sleep, Life Quality among GERD Patients

open access: yesThe Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2023
Background: Gastroesophageal reflux disease (GERD) is characterized with acid reflux, therefore may lead to esophagitis. Acid reflux may cause night symptom of GERD, therefore resulting in decreased sleep and life quality. Gastroesophageal reflux disease
Andrew Waleleng   +4 more
doaj   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

open access: yesAdvanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia   +6 more
wiley   +1 more source

Foregut microbiome in development of esophageal adenocarcinoma [PDF]

open access: yes, 2010
Esophageal adenocarcinoma (EA), the type of cancer linked to heartburn due to gastroesophageal reflux diseases (GERD), has increased six fold in the past 30 years. This cannot currently be explained by the usual environmental or by host genetic factors.
Aaron Tenney   +27 more
core   +2 more sources

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen   +12 more
wiley   +1 more source

Integrating AI with Advanced Hyperspectral Imaging for Enhanced Classification of Selected Gastrointestinal Diseases

open access: yesBioengineering
Ulcerative colitis, polyps, esophagitis, and other gastrointestinal (GI) diseases significantly impact health, making early detection crucial for reducing mortality rates and improving patient outcomes.
Chu-Kuang Chou   +9 more
doaj   +1 more source

Pharmaceutical emulsion with increased viscosity for local use of glucocorticosteroids in the esophagus [PDF]

open access: yesFarmacja Polska, 2020
Background The pharmaceutical recipe allows to improve formulations for special medical indications. In the medical environment, the appeal for new pharmaceutical forms for already known active substances is evident.
Alicja Bieńkowska   +6 more
doaj   +1 more source

Impact of Body Weight Loss During Preoperative Chemoradiotherapy on Prognosis of Patients With Lower Rectal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The present study aimed to investigate the relationship between changes in body weight and composition during chemoradiotherapy, such as the psoas muscle mass index, visceral fat index, and subcutaneous fat index obtained from computed tomography images, and long‐term outcomes in rectal cancer patients.
Shinya Abe   +9 more
wiley   +1 more source

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