Results 31 to 40 of about 23,613 (235)

Différences et similitudes des promotions industrielles et des promotions institutionnelles [PDF]

, 2006
Parallèlement à l’évolution du cadre réglementaire de la recherche clinique, l’Assistance Publique-Hôpitaux de Paris a conçu à partir de décembre 2000 une approche pragmatique du suivi des études à promotion institutionnelle.
Daurat, Véronique, Ménard, Joël
core   +1 more source

Mechanisms underlying the protective effects of San‐Bai decoction against UV radiation on the skin

International Journal of Cosmetic Science, EarlyView.
Combining conventional differential expression analysis with differential network analysis offers a promising strategy to uncover the mechanistic basis of the holistic benefits provided by herbal blends. Our findings demonstrated that San‐Bai decoction modulates multiple pathways—not only those related to skin pigmentation, such as ET‐1 signalling, but
Rui Zhang, Hong Zhang, Chengming Zhang, Wencai Jiang, Luonan Chen, Yimei Tan, Ying Zou, Xuelan Gu   +7 more
wiley   +1 more source

Caractérisation multi-échelle d'alliages nickel – titane utilisés pour des limes endodontiques

MATEC Web of Conferences, 2013
L'analyse des comportements mécaniques, biologiques et physiques aux interfaces de biomatériaux médicaux ayant vocation à évoluer dans la sphère orale est particulièrement importante.
Serres N., Bahlouli N., Hemmerlé J., Wagner-Kocher C., de Magalhaes Correia P., Fabre R., Jordan L., Haikel Y., Feugeas F.   +8 more
doaj   +1 more source

Persistent Hyperglycaemia and Transient Dysglycaemia in Tuberculosis: Evaluating the Bidirectional Interaction With Type‐2 Diabetes Mellitus and Clinical Outcomes

Tropical Medicine &International Health, Volume 31, Issue 4, Page 523-531, April 2026.
ABSTRACT Introduction Poor glycaemic control, indicated by a haemoglobin A1c (HbA1c) level of 7% or higher, increases the risk of active tuberculosis (TB) in patients with diabetes, while active TB can worsen glucose tolerance and insulin resistance, contributing to type‐2 diabetes mellitus (DM) progression.
Augustine Asare Boadu, Prince Asare, Michelle Yeboah‐Manu, Stephen Osei‐Wusu, Emelia Danso Konadu, Adwoa Asante‐Poku, Yayra Klinogo, Abraham Adjei, Desmond Omane Acheampong, Jane S. Afriyie‐Mensah, Dorothy Yeboah‐Manu, Yacoba Atiase   +11 more
wiley   +1 more source

Éthique dans les essais cliniques [PDF]

médecine/sciences, 2007
Ethics in biomedical research took off from the 1947 Nuremberg Code to its own right in the wake of the Declaration of Helsinki in 1964. Since then, (inter)national regulations and guidelines providing a framework for clinical studies and protection for study participants have been drafted and implemented, while ethics committees and drug evaluation ...
openaire   +1 more source

Evidences That Host Genetic Background More Than the Environment Shapes the Microbiota of the Snail Bulinus truncatus, an Intermediate Host of Schistosoma Species

Molecular Ecology, Volume 35, Issue 6, March 2026.
ABSTRACT Microbiota have emerged as fundamental regulators of host physiology, shaping both ecological interactions and evolutionary trajectories. Yet, the determinants of microbiota diversity and structure in wild populations—particularly the respective roles of host genetics and environmental context—are still poorly understood.
Mathilde J. Jaquet, Philippe Douchet, Eve Toulza, Thierry Lefevre, Bruno Senghor, Jérôme Boissier, Olivier Lepais, Emilie Chancerel, Benjamin Gourbal, Olivier Rey   +9 more
wiley   +1 more source

Le vaccin antipaludique RTS,S/AS01 chez les enfants âgés de 5 à 17 mois au moment de la première vaccination

The Pan African Medical Journal, 2018
Le vaccin antipaludique RTS,S/AS01 a reçu un avis scientifique favorable de l'Agence Européenne des Médicaments (EMA) en Juillet 2015. L'Organisation Mondiale de la Santé (OMS) a recommandé l'introduction pilote de ce vaccin chez des enfants âgés d'au ...
Pascale Vandoolaeghe, Lode Schuerman
doaj   +1 more source

Stratégies vaccinales contre le mélanome [PDF]

, 2006
Le mélanome est une pathologie de plus en plus fréquente, sévère, pour laquelle les traitements antitumoraux standards sont peu efficaces. Étant donné la chimiorésistance et la radiorésistance intrinsèque de cette tumeur, d’une part, et d’autre part l ...
Ghiringhelli, François, Zitvogel, Laurence   +1 more
core   +1 more source

Diagnostic Concordance of Two‐ and Three‐Gene SARS‐CoV‐2 Molecular Assays in Cameroon: Implications for Efficient Pandemic Response in Low‐ and Middle‐Income Countries

Journal of Clinical Laboratory Analysis, Volume 40, Issue 4, February 2026.
This study assessed the interoperability of DaAn Gene, ThermoFisher, and GeneXpert assays used for COVID‐19 testing in Cameroon. GeneXpert showed higher diagnostic performance over ThermoFisher, with all assays having excellent agreement at high viral loads (CT < 20).
Aurelie Minelle Kengni Ngueko, Sandrine Claire Djupsa Ndjeyep, Ezechiel Ngoufack Jagni Semengue, Alex Durand Nka, Collins Ambe Chenwi, Aude Christelle Ka'e, Yagai Bouba, Jeremiah Efakika Gabisa, Evariste Molimbou, Naomi‐Karell Etame, Tatiana Anim‐Keng Tekoh, Rachel Audrey Nayang Mundo, Pamela Patricia Tueguem, Vincent Kamael Mekel, Hugues Mba, Désiré Takou, Grace Angong Beloumou, Michel Carlos Tommo Tchouaket, Larissa Gaelle Moko Fotso, Derrick Tambe Ayuk, Christian Ngongang Ouankou, Claudia Alteri, Luna Colagrossi, Yap Boum II, Halle Gregory Eddy Ekane, Francesca Ceccherini‐Silberstein, Vittorio Colizzi, Nicaise Ndembi, Alfred K. Njamnshi, Alexis Ndjolo, Carlo‐Federico Perno, Maria‐Mercedes Santoro, Joseph Fokam   +32 more
wiley   +1 more source

LDL apheresis as an alternate method for plasma LPS purification in healthy volunteers and dyslipidemic and septic patients

Journal of Lipid Research, 2020
Lipopolysaccharide (LPS) is a key player for innate immunity activation. It is therefore a prime target for sepsis treatment, as antibiotics are not sufficient to improve outcome during septic shock.
Auguste Dargent, Jean-Paul Pais de Barros, Samir Saheb, Randa Bittar, Wilfried Le Goff, Alain Carrié, Thomas Gautier, Isabelle Fournel, Anne Laure Rerole, Hélène Choubley, David Masson, Laurent Lagrost, Jean-Pierre Quenot   +12 more
doaj   +1 more source