Results 241 to 250 of about 1,599,716 (308)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Qualitative hypotheses. [PDF]

Open Res Eur
Karhulahti VM.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Growing Professionals: Exploring the Impact of a Professional Identity Formation Curriculum in Medical School. [PDF]

J Med Educ Curric Dev
Altshuler L, Tewksbury L, Buckvar-Keltz L, Wargo E, Kalet A.   +4 more
europepmc   +1 more source

Should I Have to Pay to Work? On Responsibility for the Cost of Disability Accommodations. [PDF]

Disabil Soc
Mintz KT.
europepmc   +1 more source

Essays on and in the Chicago Tradition - A Review Essay

Journal of Money, Credit and Banking, 1984
openaire   +1 more source

Reparations not remuneration: Redefining the future of lived experience. [PDF]

PLOS Ment Health
Sharma P.
europepmc   +1 more source

Artificial intelligence assisted automated short answer question scoring tool shows high correlation with human examiner markings. [PDF]

BMC Med Educ
Seneviratne HMTW, Manathunga SS.
europepmc   +1 more source

Popuhnul je tihi vetar... tihi vetar od zajika

Zbornik Lovranšćine, 2014
Cvjetana Miletić
doaj  

Platform gentrification: The production of urban inequalities in the on-demand city. [PDF]

Open Res Eur
Sequera J.
europepmc   +1 more source