Results 161 to 170 of about 484,976 (246)
Essential Oils from Pruning Residues of <i>Lavandula angustifolia</i> Mill. 'Essence Purple' and <i>Helichrysum italicum</i> (Roth) G.Don: Phytotoxic and Ecotoxicological Evaluation. [PDF]
Malaspina P +6 more
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Medical Colleges Have an Obligation to Ensure Full Participation in Clinical Quality Registries. [PDF]
Aitken RJ, Smith JA, Maddern GJ.
europepmc +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Regarding Clinical Management of Polyposis: Do You Mind? [PDF]
Sengul I, Sengul D.
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Computational Discovery and Optimization of a Potent, Selective, and Drug-Like Scaffold for p38α Inhibition. [PDF]
Nelen J +6 more
europepmc +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular glues: Recent advances in cereblon substrate identification and mechanistic insights. [PDF]
Guan Q +5 more
europepmc +1 more source

