Results 31 to 40 of about 96,674 (258)

Independent Quality Assessment of Essential Climate Variables: Lessons Learned from the Copernicus Climate Change Service

Bulletin of the American Meteorological Society, 2022
Abstract If climate services are to lead to effective use of climate information in decision-making to enable the transition to a climate-smart, climate-ready world, then the question of trust in the products and services is of paramount importance. The Copernicus Climate Change Service (C3S) has been actively grappling with how to build such trust ...
Yang, Chunxue, Cagnazzo, Chiara, Artale, Vincenzo, Nardelli, Bruno Buongiorno, Buontempo, Carlo, Busatto, Jacopo, Caporaso, Luca, Cesarini, Claudia, Cionni, Irene, Coll, John, Crezee, Bas, Cristofanelli, Paolo, de Toma, Vincenzo, Essa, Yassmin Hesham, Eyring, Veronika, Fierli, Federico, Grant, Luke, Hassler, Birgit, Hirschi, Martin, Huybrechts, Philippe, Le Merle, Eva, Leonelli, Francesca Elisa, Lin, Xia, Madonna, Fabio, Mason, Evan, Massonnet, Francois, Marcos, Marta, Marullo, Salvatore, Muller, Benjamin, Obregon, Andre, Organelli, Emanuele, Palacz, Artur, Pascual, Ananda, Pisano, Andrea, Putero, Davide, Rana, Arun, Sanchez-Roman, Antonio, Seneviratne, Sonia, Serva, Federico, Storto, Andrea, Thiery, Wim, Throne, Peter, Van Tricht, Lander, Verhaegen, Yoni, Volpe, Gianluca, Santoleri, Rosalia   +45 more
openaire   +5 more sources

The novel GOME-type Ozone Profile Essential Climate Variable (GOP-ECV) data record covering the past 26 years [PDF]

Atmospheric Measurement Techniques
We present the Global Ozone Monitoring Experiment (GOME)-type Ozone Profile Essential Climate Variable (GOP-ECV) data record covering the 26-year period from July 1995 until October 2021.
M. Coldewey-Egbers, D. G. Loyola R., B. Latter, B. Latter, R. Siddans, R. Siddans, B. Kerridge, B. Kerridge, D. Hubert, M. van Roozendael, M. Eisinger   +10 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Independent Quality Assessment of Essential Climate Variables

, 2022
If climate services are to lead to effective use of climate information in decision-making to enable the transition to a climate-smart, climate-ready world, then the question of trust in the products and services is of paramount importance. The Copernicus Climate Change Service (C3S) has been actively grappling with how to build such trust: provision ...
Yang C, Cagnazzo C, Artale V, Nardelli BB, Buontempo C, Busatto J, Caporaso L, Cesarini C, Cionni I, Coll J, Crezee B, Cristofanelli P, de Toma V, Essa YH, Eyring V, Fierli F, Grant L, Hassler B, Hirschi M, Huybrechts P, Le Merle E, Leonelli FE, Lin X, Madonna F, Mason E, Massonnet F, Marcos M, Marullo S, Muller B, Obregon A, Organelli E, Palacz A, Pascual A, Pisano A, Putero D, Rana A, SanchezRoman A, Seneviratne SI, Serva F, Storto A, Thiery W, Throne P, Van Tricht L, Verhaegen Y, Volpe G, Santoleri R   +45 more
openaire   +2 more sources

Reviewing the discoverability and accessibility to data and information products linked to Essential Climate Variables [PDF]

International Journal of Digital Earth, 2019
Essential Climate Variables (ECVs) are geophysical records generated from systematic Earth Observations associated with climate variations, changes, and impacts. ECVs products support the data and information needs of international frameworks and policies such as the work of the United Nations Framework Convention on Climate Change (UNFCCC) and the ...
Miranda Espinosa, Maria Teresa, Giuliani, Gregory, Ray, Nicolas   +2 more
openaire   +3 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Weather, not climate, defines distributions of vagile bird species. [PDF]

PLoS ONE, 2010
BackgroundAccurate predictions of species distributions are essential for climate change impact assessments. However the standard practice of using long-term climate averages to train species distribution models might mute important temporal patterns of ...
April E Reside, Jeremy J Vanderwal, Alex S Kutt, Genevieve C Perkins   +3 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Evaluation of a Global Soil Moisture Product from Finer Spatial Resolution SAR Data and Ground Measurements at Irish Sites

Remote Sensing, 2014
In the framework of the European Space Agency Climate Change Initiative, a global, almost daily, soil moisture (SM) product is being developed from passive and active satellite microwave sensors, at a coarse spatial resolution.
Chiara Pratola, Brian Barrett, Alexander Gruber, Gerard Kiely, Edward Dwyer   +4 more
doaj   +1 more source