Results 191 to 200 of about 1,085,609 (304)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Multifaceted and educational interventions to improve prescribing indicators in the Middle East and North Africa Region: a systematic review and meta-analysis. [PDF]

Int J Clin Pharm
Ilyas M, Chivese T, Hadi MA, Ncube NBQ, Khan MN.   +4 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Global patenting of 'essential' drugs [PDF]

, 2000
Goldman, Philip M.
core  

Are drugs for rare diseases "essential"?

Bulletin of the World Health Organization
Marcus M Reidenberg
doaj   +1 more source

Potentially Hazardous Drugs in the Paediatric ICU: A Narrative Review on the Exemplary Cases of Propofol, Chloramphenicol, and Acetylsalicylic Acid. [PDF]

Children (Basel)
Beckers L, Verbruggen J, Saldien V, De Dooy J, van Zanten E, Peros T, Wiggelinkhuizen M, Jorens PG.   +7 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Supply Chain Events and Risk of Drug Shortage in Canada.

JAMA Netw Open
Santhireswaran A, Ho MKH, Kim KC, Chaudhry S, Suda KJ, Gaudette E, Burry L, Tadrous M.   +7 more
europepmc   +1 more source

Obstetric and Emergency Anesthesia in Somalia: Patient Safety Challenges in a Fragile Health System. [PDF]

Int J Womens Health
Mohamed IA.
europepmc   +1 more source

[Essential drugs].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1989
openaire   +1 more source