Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Antibody-drug conjugates for infectious and neglected tropical diseases: chemical design principles, target biology, and translational challenges. [PDF]
Reddy D +3 more
europepmc +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Applications of Selected Nanoencapsulated Indigenous Essential Oils in Medicine, Food, and Agriculture: A Review. [PDF]
Wutu OS, Mpambani B, Naidoo CM.
europepmc +1 more source
693 drugs in essential drugs list.
openaire +1 more source
Editorial: Optimizing medication management in older adults: addressing polypharmacy, deprescribing and represcribing challenges. [PDF]
Garfinkel D, Wehling M, Scott I.
europepmc +1 more source
Phytochemistry and Pharmacological Properties of Medicinal Plants. [PDF]
Maroyi A.
europepmc +1 more source
A strategic discovery roadmap towards high-quality leads and drug development candidates for kinetoplastid diseases. Part 3: from lead towards a drug development candidate. [PDF]
Hendrickx S +19 more
europepmc +1 more source

