Results 61 to 70 of about 1,949,102 (353)
Background: The evaluation of internationally comparable indicators of medicine use is important to devise strategies to promote the rational use of medicines (RUM).
Nikhil Verma +4 more
doaj +1 more source
Antiretroviral medications for pediatric use in the context of the Unified Health System: are there therapeutic gaps in Brazil? [PDF]
Objective: To evaluate the incorporation and adequacy of antiretrovirals for the treatment of HIV in children within the context of the Unified Health System in Brazil.
Suelen Martins da Costa +1 more
doaj +1 more source
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez +13 more
wiley +1 more source
OBJETIVO: Generar un diagnóstico sobre la disponibilidad de algunos medicamentos esenciales del Cuadro Básico de Insumos (CBI) en las unidades de primer nivel de atención de la Secretaría de Salud en el estado de Tamaulipas, México.
Cristela Reséndez +2 more
doaj
An organometallic compound which exhibits a DNA topology-dependent one-stranded intercalation mode [PDF]
Understanding how small molecules interact with DNA is essential since it underlies a multitude of pathological conditions and therapeutic interventions.
Adhireksan +16 more
core +2 more sources
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell +14 more
wiley +1 more source
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher +8 more
wiley +1 more source
Challenges and Achievements of Promoting Rational Use of Drugs in Iran [PDF]
Rational use of drugs is one of the major issues in health systems. Analyzing the prescriptions would be of help in recognition of physicians' behavior and population beliefs.
F Soleymani +2 more
doaj +1 more source
Background Good inventory management practices in the health facilities are one of the critical aspects that influence the availability of essential medicines (EMs). This study aimed to assess EMs availability and inventory management practices at health
Adane Teshome Kefale +1 more
doaj +1 more source

