Results 41 to 50 of about 2,992,939 (247)

Identification of a novel enhancer of CEBPE essential for granulocytic differentiation [PDF]

Blood, 2019
Abstract CCAAT/enhancer binding protein ε (CEBPE) is an essential transcription factor for granulocytic differentiation. Mutations of CEBPE occur in individuals with neutrophil-specific granule deficiency (SGD), which is characterized by defects in neutrophil maturation.
Pavithra Shyamsunder, Mahalakshmi Shanmugasundaram, Anand Mayakonda, Pushkar Dakle, Weoi Woon Teoh, Lin Han, Deepika Kanojia, Mei Chee Lim, Melissa Fullwood, Omer An, Henry Yang, Jizhong Shi, Mohammad Zakir Hossain, Vikas Madan, H. Phillip Koeffler   +14 more
openaire   +2 more sources

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Scaling enterprise AI in healthcare: the role of governance in risk mitigation frameworks

npj Digital Medicine
This perspective article examines the role of governance frameworks in mitigating risks and building trust in AI implementations within healthcare organizations.
Andreea Bodnari, John Travis
doaj   +1 more source

Collision Avoidance Capabilities in High-Density Airspace Using the Universal Access Transceiver ADS-B Messages

Drones
The safe integration of a large number of unmanned aircraft systems (UASs) into the National Airspace System (NAS) is essential for advanced air mobility.
Coulton Karch, Jonathan Barrett, Jaron Ellingson, Cameron K. Peterson, V. Michael Contarino   +4 more
doaj   +1 more source

Harnessing Nanotechnology to Enhance Essential Oil Applications

Molecules
Essential oils (EOs) are versatile natural compounds with significant antimicrobial, antioxidant, antifungal, and therapeutic properties, making them valuable in industries such as food preservation, agriculture, and healthcare. However, their inherent volatility, low water solubility, and susceptibility to environmental degradation limit their direct ...
Hossein Omidian, Luigi X. Cubeddu, Erma J. Gill   +2 more
openaire   +3 more sources

Enhanced antinatriuresis in response to angiotensin II in essential hypertension [PDF]

American Journal of Hypertension, 2000
Angiotensin II regulates sodium homeostasis by modulating aldosterone secretion, renal vascular response, and tubular sodium reabsorption. We hypothesized that the antinatriuretic response to angiotensin II is enhanced in human essential hypertension.
A U, Klingbeil, J, Jacobi, M R, Langenfeld, S, John, K F, Hilgers, R E, Schmieder   +5 more
openaire   +2 more sources

Provider and Parent Perspectives on Prioritizing the “Asking and Monitoring” Pediatric Cancer Psychosocial Standards of Care

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager, Natalie Koskela‐Staples, Emily M. Pariseau, Michele Scialla, Kimberly Buff, Lori Wiener, Victoria Sardi Brown, Anne E. Kazak, Kimberly S. Canter   +8 more
wiley   +1 more source

ShinyAnonymizer Enhanced Version and Beyond: A Further Exploration of Privacy-Preserving Solutions in Health Data Management

Applied Sciences
Healthcare institutions generate massive amounts of valuable patient data in the digital age. Finding the right balance between patient privacy and the demand for data-driven medical enhancements is essential.
Marios Vardalachakis, Nikos Papadakis, Manolis Tampouratzis   +2 more
doaj   +1 more source

Enhanced Antibacterial Effects of Clove Essential Oil by Nanoemulsion

Journal of Oleo Science, 2014
The aim of present study was to develop and evaluate nanoemulsion formulations of clove essential oil (CEO) for its antibacterial effects in comparison with pure CEO and standard amikacin antibiotic (positive control). Different nanoemulsions of CEO were developed by aqueous phase titration method via construction of pseudo-ternary phase diagrams and ...
Anwer, Md Khalid, Jamil, Shahid, Ibnouf, Elmutasim Osman, Shakeel, Faiyaz   +3 more
openaire   +3 more sources

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source