Results 191 to 200 of about 4,393,589 (384)

Oxygen support of physical stress in perindopril-treated hypertensive patients

open access: yesКардиоваскулярная терапия и профилактика, 2005
Aim. To study and assess, with spiroergometry method, main parameters of physical stress (PS) oxygen (O2) support in arterial hypertension (AH) patients receiving combined and monotherapy with an ACE inhibitor perindopril. Material and methods. The study
V. I. Makolkin   +3 more
doaj  

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

open access: yesAdvanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai   +5 more
wiley   +1 more source

Bispecific Antibody Targeting VEGF/TGF‐β Synergizes with Local Radiotherapy: Turning Tumors from Cold to Inflamed and Amplifying Abscopal Effects

open access: yesAdvanced Science, EarlyView.
Y332D, a bispecific antibody that simultaneously blockades VEGF and TGF‐β, counteracted negative RT effects that are attributed to the upregulation of TGF‐β and VEGF, as well as further enhanced the immunostimulatory effects of RT, thereby reprograming the TME from immune “cold” to inflamed state and forming an effective in‐situ vaccine that eradicate ...
Lijuan Lyu   +13 more
wiley   +1 more source

FEATURES OF BLOOD PRESSURE DAILY PROFILE IN PATIENTS WITH ARTERIAL HYPERTENSION AND IDDM AS ASSESSED BY DAILY BLOOD PRESSURE MONITORING

open access: yesРоссийский кардиологический журнал, 2002
We have conducted the research on revealing conformities of daily profile patients with arterial hypertension with non-insulin-dependent diabetes mellitus as compared with the patients of essential hypertension according to returns of daily blood ...
G. B. Selivanova, A. P. Borisenko
doaj  

Hemodynamic Patterns in Essential Hypertension [PDF]

open access: bronze, 1965
Samuel Finkielman   +2 more
openalex   +1 more source

HIF2α–arginase axis is essential for the development of pulmonary hypertension

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2016
A. Cowburn   +10 more
semanticscholar   +1 more source

The GRK2/AP‐1 Signaling Axis Mediates Vascular Endothelial Dysfunction and Atherosclerosis Induced by Oscillatory Low Shear Stress

open access: yesAdvanced Science, EarlyView.
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu   +18 more
wiley   +1 more source

Diagnostic Value of Let-7a-5p in Essential Hypertension. [PDF]

open access: yesJ Clin Hypertens (Greenwich)
Wang L, Zhu Q, Cheng B, Jiang N, Dong C.
europepmc   +1 more source

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