Results 41 to 50 of about 683,747 (361)
The Pathophysiology and Treatment of Hypertension in Patients With Cushing's Syndrome [PDF]
When hypertension, a pathology that is frequently found in the general population, presents in a young patient, secondary causes such as Cushing's syndrome (CS), a rare disease characterized by long-term elevated cortisol levels, should be considered ...
Barbot, Mattia+2 more
core +1 more source
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad+13 more
wiley +1 more source
Background Hypertension is an important risk factor for cardiovascular disease, even in the elderly. Fimasartan is a new non-peptide angiotensin II receptor blocker with a selective type I receptor blocking effect.
Min-gu Kang+24 more
doaj +1 more source
Correction to the pathogenic alternative splicing, caused by the common GNB3 c.825C>T allele, using a novel, antisense morpholino [PDF]
The very common GNB3 c.825C>T polymorphism (rs5443), is present in approximately half of all human chromosomes. Significantly the presence of the GNB3 825T allele has been strongly associated, with predisposition to essential hypertension ...
Lester, Douglas H.+2 more
core +3 more sources
Sample Size in Natural Language Processing within Healthcare Research [PDF]
Sample size calculation is an essential step in most data-based disciplines. Large enough samples ensure representativeness of the population and determine the precision of estimates. This is true for most quantitative studies, including those that employ machine learning methods, such as natural language processing, where free-text is used to generate
arxiv
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
PPG Signals for Hypertension Diagnosis: A Novel Method using Deep Learning Models [PDF]
Hypertension is a medical condition characterized by high blood pressure, and classifying it into its various stages is crucial to managing the disease. In this project, a novel method is proposed for classifying stages of hypertension using Photoplethysmography (PPG) signals and deep learning models, namely AvgPool_VGG-16.
arxiv
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
Pediatric endocrine hypertension
Endocrine causes of hypertension are rare in children and screening for endocrine hypertension in children should be carried out only after ruling out renal and renovascular causes.
Nisha Bhavani
doaj +1 more source
Hypertension effects 30% of the total population with incidences higher in socioeconomically deprived areas. This nurse will research the pathophysiology of essential hypertension to gain a thorough understanding of the disease and provide evidence based
Rodriguez- Tercius, Melinda
core +1 more source