Results 281 to 290 of about 6,492,121 (341)

A Quantitative Review of Brain Activation Maps for Mentalizing, Empathy, and Social Interactions: Specifying Commonalities and Differences. [PDF]

Behav Sci (Basel)
Kranewitter B, Schurz M.
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Identification of flood vulnerability areas using analytical hierarchy process techniques in the Wuseta watershed, Upper Blue Nile Basin, Ethiopia. [PDF]

Sci Rep
Mulu A, Kassa SB, Wossene ML, Adefris S, Meshesha TM.   +4 more
europepmc   +1 more source

Pseudo-Developing Maps for Ideal Triangulations I: Essential Edges and Generalised Hyperbolic Gluing Equations

, 2011
Henry Segerman, Stephan Tillmann
openalex   +2 more sources

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Bayesian spatiotemporal stochastic partial differential equation for high-resolution earthquake magnitude mapping: Application to Sumatra Island, Indonesia. [PDF]

MethodsX
Azuri DF, Jaya IGNM, Rosandi Y.
europepmc   +1 more source

MAP-Kinase Regulated Cytosolic Phospholipase A2 Activity Is Essential for Production of Infectious Hepatitis C Virus Particles

, 2012
Nicolas Menzel, Wolfgang Fischl, Kathrin Hueging, Dorothea Bankwitz, Anne Frentzen, Sibylle Haid, Juliane Gentzsch, Lars Kaderali, Ralf Bartenschlager, Thomas Pietschmann   +9 more
openalex   +2 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Prevalence, associated risk factors and satellite imagery analysis in predicting soil-transmitted helminth infection in Nakhon Si Thammarat Province, Thailand. [PDF]

Sci Rep
Muenjak J, Thongrod J, Choodamdee C, Pongpanitanont P, Yingklang M, Thanchomnang T, Laymanivong S, Janwan P.   +7 more
europepmc   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source