Results 141 to 150 of about 195,292 (253)

Mapping the therapeutic versatility of WHO essential medicines: a systematic analysis of off-label indications. [PDF]

Ther Adv Drug Saf
Kateel R, Hegde S, Holla S.
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Global mechanisms to improve affordability of high-priced medicines: the role of the WHO model lists of essential medicines. [PDF]

J Pharm Policy Pract
Jenei K.
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Access to essential medicines during the Sudanese civil war: a cross-sectional study. [PDF]

Int J Equity Health
Ahmed ABM, Hemmeda L, Alrawa S, Abukhris DKH, Suliman DKEE, Hamad E, Mohammed FAA, Gasm Alseed Fadlalmoula GAA, Rhamttallah M, Awadalla Alsedig MF, Awad MH, Masaad Ahmed MB, Abaker Joda TA.   +12 more
europepmc   +1 more source

Shortages of inexpensive essential medicines

The Lancet Oncology, 2019
Vyas, Malvika, de Vries, Elisabeth G. E., Casali, Paolo G., Tabernero, Josep   +3 more
openaire   +3 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

WHO essential medicines for reproductive health

BMJ Global Health, 2019
Fernando Althabe, Roopan Gill, Bela Ganatra   +2 more
doaj   +1 more source

Economic assessment of potential changes to essential medicines for diabetes in Uganda. [PDF]

PLoS One
Bonyani A, Lin TK, Jakira A, Kimera ID, Muddu M, Schwartz JI, Kahn JG.   +6 more
europepmc   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source