Results 61 to 70 of about 449,097 (277)

Cryptococcal meningitis: improving access to essential antifungal medicines in resource-poor countries [PDF]

, 2013
Cryptococcal meningitis is the leading cause of adult meningitis in sub-Saharan Africa, and contributes up to 20% of AIDS-related mortality in low-income and middle-income countries every year.
Bicanic, Tihana, Chiller, Tom, Easterbrook, Philippa, Ford, Nathan, Govender, Nelesh, Harrison, Thomas S, Loyse, Angela, Roy, Monika, Thangaraj, Harry   +8 more
core   +1 more source

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

The impact of the Medicines Control Council backlog and fast-track review system on access to innovative and new generic and biosimilar medicines of public health importance in South Africa [PDF]

, 2016
The fast-track registration policy of the South African National Department of Health allows for rapid registration of new medicines of public health importance and of all medicines on the Essential Medicines List, most of which are generics. No limit is
Leng, HMJ, Pollock, AM, Sanders, D
core   +3 more sources

Radiotherapy Delivery in Deep Inspiration for Pediatric Patients—Final Results of the Phase II Feasibility Study TEDDI

Pediatric Blood &Cancer, EarlyView.
Abstract Introduction The TEDDI trial tested the feasibility and reproducibility of deep‐inspiration breath‐hold (DIBH) in pediatric patients referred for radiotherapy. This report presents final results, including patient‐reported outcomes (PRO) and dosimetric comparison of DIBH and free‐breathing (FB).
Daniella Elisabet Østergaard, Anni Young Lundgaard, Laura Ann Rechner, Danijela Dejanovic, Hanne Krogh Rose, Jolanta Hansen, Leila Vaalavirta, Miia Mokka, Marianne Aznar, Peder Skov Wehner, Lisa Lyngsie Hjalgrim, Maja Vestmø Maraldo   +11 more
wiley   +1 more source

Selection of essential medicines for diabetes in low and middle income countries: a survey of 32 national essential medicines lists. [PDF]

PLoS ONE, 2014
AIM: Diabetes is a growing burden especially in low and middle income countries (LMICs). Inadequate access to diabetes care is of particular concern and selection of appropriate diabetes medicines on national essential medicines lists (NEMLs) is a first ...
Yaser T Bazargani, Anthonius de Boer, Hubert G M Leufkens, Aukje K Mantel-Teeuwisse   +3 more
doaj   +1 more source

Health-industry linkages for local health: reframing policies for African health system strengthening [PDF]

, 2018
The benefits of local production of pharmaceuticals in Africa for local access to medicines and to effective treatment remain contested. There is scepticism among health systems experts internationally that production of pharmaceuticals in sub-Saharan ...
ACT Watch Group, African Union, African Union, African Union, African Union, Aldis, Battams, Berger, Bigdeli, Boschma, Chataway, Chaudhuri, Cohen, Commission on Social Determinants of Health (CSDH), Dinh, East African Community (EAC), Eriksen, Ernst, Ewen, Federal Democratic Republic of Ethiopia (FDRE), Flahault, Gebre-Mariam, Geoffrey Banda, Giddens, Government of Kenya, Government of Uganda, Hahn, Horton, Institute for Health Metrics and Evaluation (IHME), Jires Tunguhole, Julius Mugwagwa, Kaplan, Kaplan, Koplan, Kumar, Lin, Lopes, Macfarlane, Mackintosh, Mackintosh, Mackintosh, Malmberg, Maureen Mackintosh, Mercy Karimi Njeru, Ministry of Industry (MIT) and UNIDO, Morris, Mujinja, Nadvi, Ozawa, Paula Tibandebage, Ravix, Republic of Ghana, Republic of Kenya, Rowson, Rushton, Samuel Wangwe, Schmitz, Seiter, Shadlen, Sheikh, Shiffman, Sidibé, Srinivas, Sutton, UNCTAD, United Nations (UN), United Republic of Tanzania (URT), United Republic of Tanzania (URT), Waako, Wagner, West, WHO/World Bank, Wiedenmayer, Wilson, Wirtz, World Health Organisation (WHO), World Health Organisation (WHO), World Health Organisation (WHO), World Health Organisation (WHO), World Health Organisation (WHO), Yadav, Yadav   +81 more
core   +3 more sources

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Cost-effectiveness analysis of flucytosine as induction therapy in the treatment of cryptococcal meningitis in HIV-infected adults in South Africa

BMC Health Services Research, 2021
Background Cryptococcal meningitis in HIV-infected patients in sub-Saharan Africa accounts for three-quarters of the global cases and 135,000 deaths per annum. Current treatment includes the use of fluconazole and amphotericin B.
Jacqui Miot, Trudy Leong, Simbarashe Takuva, Andrew Parrish, Halima Dawood   +4 more
doaj   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source