Results 181 to 190 of about 7,341,045 (287)

Women's multidimensional empowerment index and essential newborn care practice in Bangladesh: The mediating role of skilled antenatal care follow-ups. [PDF]

PLoS One, 2023
Sen KK, Jamee AR, Bari W.
europepmc   +1 more source

Arhgef1 Deletion Disrupts Early Cortical Neurogenesis via PAK1 Overactivation and Causes Motor Dysfunction in Adulthood

Advanced Science, EarlyView.
ARHGEF1 plays a pivotal role in both embryonic cortical neurogenesis and adult motor function. During early development, it governs genesis of deep‐layer cortical neurons by negatively regulating RAC1/CDC42‐PAK1‐Cofilin signaling. In adulthood, ARHGEF1 is important for the maintenance of neuronal morphology and activity in the motor cortex, ensuring ...
Liuren Li, Xuanyue Ma, Zhenyu Ding, Bang Sun, Linglin Liu, Hei Matthew Yip, Wei Wang, Tianying Wu, Yuan Guo, Yinghui Peng, Shiqing Zhang, Jacque Pak Kan Ip, Li Zhang, Keshen Li, Lei Shi   +14 more
wiley   +1 more source

Early essential newborn care: a decade of scaling up quality, life-saving interventions across East Asia and the Pacific (2013-2023). [PDF]

BMJ Glob Health
Sobel HL, Murray JCS, Mannava P, Delgermaa V, Pham HV, Li Z, Tran H, Chhour YM, Im S, Rathavy T, Kim R, Krang S, Cheang K, Phal S, Xu T, Rattana S, Singharaj V, Phrasithdeth B, Kounnavongsa O, Baldan T, Roland B, Waramin E, Salva M, Yaipupu J, Calibo AP, Constantino R, Bello M, Kitong J, Jatobatu A, Dinh TA, Tran KD, Tuan HA, Pham TQN, Orelly T, Bayandorj T, Ko E, Silvestre MA, Mason E, Obara H, Putney P, Kubota S.   +40 more
europepmc   +1 more source

Effect of the Mamás del Río programme on essential newborn care: a three-year before-and-after outcome evaluation of a community-based, maternal and neonatal health intervention in the Peruvian Amazon. [PDF]

Lancet Reg Health Am, 2023
Blas MM, Reinders S, Alva A, Neuman M, Lange I, Huicho L, Ronsmans C.   +6 more
europepmc   +1 more source

Melatonin Mitigates Doxorubicin‐Induced Cardiotoxicity by Targeting the USP18/PKM2 Axis Without Compromising Antitumor Efficacy

Advanced Science, EarlyView.
Melatonin engages MT1/MT2 receptors to suppress STAT1‐driven USP18 upregulation, thereby redirecting PKM2 ubiquitination from K33‐linked autophagic degradation toward K27‐linked nuclear translocation. This prevents PKM2‐mediated proinflammatory gene expression in the heart, alleviating doxorubicin‐induced cardiotoxicity without compromising antitumor ...
Zhenyu Feng, Yijin Yang, Jie Bai, Pengqi Sun, Xuyang Sun, Jinshu Shang, Yang Liu, Zhen Ning, Ningning Zhang, Yun‐long Xia, Yunpeng Xie   +10 more
wiley   +1 more source

Implementation of essential newborn care in settings of high-intensity armed conflict: a systematic review. [PDF]

BMJ Glob Health
Moutwakil A, Kumar A, Li AT, Huang CJ, Nelson BD, Woodward A, Amsalu R, Darmstadt GL, Mediratta RP.   +8 more
europepmc   +1 more source

CKMT1 Counteracts VDAC1 Oligomerization‐Induced Neuronal Pyroptosis Through Steric Hindrance in Ischemic Stroke

Advanced Science, EarlyView.
CKMT1 inhibits VDAC1 oligomerization via a dual‐region mechanism: its NTD interacts with the VDAC1 C‐terminal domain, while residues 1–39 sterically hinder dimerization, thereby reducing mtDNA leakage and AIM2 inflammasome activation, suppressing neuronal pyroptosis and protecting against cerebral ischemic injury. ABSTRACT Ischemic stroke is one of the
Xiaoyu Wang, Sai Shi, Jianghui Wu, Jingge Zhang, Shuqin Li, Yuyan Hu, Haifeng Yin, Chenguang Zhao, Dong Ma, Xiaohui Xian, Lizhe Liu, Ling Zhao, Xiyun Liu, Zhikai Yu, Lihua Dong, Wenbin Li, Lingyan Zhang, Min Zhang   +17 more
wiley   +1 more source

Essential newborn care practices and determinants in Ethiopia: a multilevel analysis of national survey data. [PDF]

BMJ Open
Mekonnen TS, Delie AM, Hailu M, Mehari MG, Bizuneh GK, Mengistie BA.   +5 more
europepmc   +1 more source

Disproportionate Environmental Risks: A Descriptive Analysis of Chemical Facilities and Accidents in the United States

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Using nationwide data on the US Environmental Protection Agency's Risk Management Plan (RMP) program, we examine the proportions of underserved populations living near facilities that use extremely hazardous chemicals, both before and after accidents involving fires, explosions, and/or toxic vapors occur.
Karlee Cook, Dennis Guignet, Robin R. Jenkins, Margaret Sugg   +3 more
wiley   +1 more source

Magnitude and Determinants of Postnatal Mothers' Knowledge of Essential Newborn Care at Home in Rural Ethiopia. [PDF]

Front Pediatr, 2022
Getachew T, Dheresa M, Eyeberu A, Balis B, Yadeta TA.   +4 more
europepmc   +1 more source