Results 171 to 180 of about 855,886 (285)

Unravelling TPX2-centered co-expression networks as key drivers of aggressive prostate cancer. [PDF]

Sci Rep
Sheibani-Tezerji R, Perez Malla CU, Wasinger G, Misura K, Haase A, Malzer A, Kalla J, Tran L, Egger G.   +8 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Personalised care, youth mental health, and digital technology: A value sensitive design perspective and framework. [PDF]

Ethics Inf Technol
Poulsen A, Hickie IB, Chong MK, LaMonica HM, Turner A, Iorfino F.   +5 more
europepmc   +1 more source

Uncertainty Is the New Norm, Adaptability Is Essential

Academic Medicine, 2020
openaire   +3 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Reaction norm models for the evaluation of reproductive and productive performance in Nellore cattle. [PDF]

Trop Anim Health Prod
Menezes FL, Araújo SI, Lobo RB, Nakabashi LRM, Baldi F, Pavan NL, Seidel GCI, Araújo CV.   +7 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The Role of Aldosterone in Vascular Permeability in Diabetes. [PDF]

Cells
Aleksiejczuk M, Bielicka N, Bruzgo-Grzybko M, Kalita IS, Olichwier AJ, Mierzejewska P, Stelmaszewska J, Dzieciol J, Chabielska E, Gromotowicz-Poplawska A.   +9 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Digital twin simulations of theory-driven crisis messaging during hurricane evacuations in synthetic populations: a Miami-Dade County case study. [PDF]

Front Artif Intell
Walling B, Desens L, Howard V, O'Neill R, Scannell D, Giammarino M, Elson SB, Rosen S.   +7 more
europepmc   +1 more source