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Literature Review: Essential Thrombocythemia [PDF]
Essential Thrombocythemia (ET), a clonal hematopoietic stem cell disorder, is one of the classic Philadelphia negative myeloproliferative neoplasms and is characterized by thrombocytosis with bone marrow megakaryocytic hyperplasia.
Lawrence, Nichola +3 more
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Background Essential thrombocythemia is a chronic myeloproliferative disorder; patients with this disorder have a propensity to develop thrombosis, myelofibrosis, and leukemia.Design and Methods We studied 605 patients with essential thrombocythemia ...
Francesco Passamonti +12 more
doaj +1 more source
Adult TWIST2‐high B‐ALL confirms metabolic association but reveals molecular heterogeneity
HemaSphere, Volume 10, Issue 6, June 2026.
Wencke Walter +3 more
wiley +1 more source
Might essential thrombocythemia carry Ph anomaly?
Might essential thrombocythemia carry Ph ...
LUPPI, Mario +5 more
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To observe the effect of the new World Health Organization (WHO) criteria on the incidence of myeloproliferative neoplasms, we performed a retrospective study of a population-based registry in the Côte d’Or area, France, from 1980 to 2007. A total of 524
François Girodon +9 more
doaj +1 more source
The human myeloproliferative disorders: molecular pathogenesis and clonal heterogeneity
The classical myeloproliferative disorders (MPD), comprising essential thrombocythaemia (ET), polycythaemia vera (PV) and idiopathic myelofibrosis (IMF), are clonal premalignant haematopoietic neoplasms associated with activating mutations in signalling ...
core +2 more sources
Moyamoya syndrome in an adult with essential thrombocythemia
Moyamoya syndrome is a rare cerebrovascular disorder characterized by progressive occlusion of the supraclinoid internal carotid artery and proximal portions of the anterior and middle cerebral arteries resulting in an extensive network of collateralized
Marc Lazzaro +3 more
doaj +1 more source
Hematologic case: essential thrombocythemia
Essential Thrombocythemia (ET) is a rare disease in pediatric age. The dominant clinical manifestations are thrombotic (arterial or venous) and/or hemorrhagic, but most of the cases are asymptomatic, and diagnosis made by routine hemogram.
Lopes, R. +4 more
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Deep sequencing reveals double mutations in cis of MPL exon 10 in myeloproliferative neoplasms
Somatic mutations of MPL exon 10, mainly involving a W515 substitution, have been described in JAK2 (V617F)-negative patients with essential thrombocythemia and primary myelofibrosis.
Daniela Pietra +11 more
doaj +1 more source
Essential thrombocythemia is an uncommon disease. It involves an overproduction of megakaryocytes in the marrow. These platelets may not function normally and can cause a blockage in blood vessels and other complications. We report two cases of essential thrombocythemia with different clinical presentations.
Bhatti, Adnan Bashir +2 more
openaire +3 more sources

