Results 61 to 70 of about 3,046,243 (224)

Pretreatment with Hydroxyurea of the Patient with Essential Thrombocythemia Followed by Coronary Artery Bypass Surgery

open access: yesOman Medical Journal, 2014
The risk of thrombosis is high in patients with essential thrombocythemia. Special precaution needed for those patients who will undergo Coronary artery bypass grafting. We are reporting a 62 years old patient with ischemic heart disease who was found to
Edem Ziadinov   +3 more
doaj   +1 more source

Impact of Donor Type on Outcomes After Allogeneic Hematopoietic Cell Transplantation in Myelofibrosis: A Study on Behalf of the Chronic Malignancies Working Party of the EBMT

open access: yesAmerican Journal of Hematology, Volume 100, Issue 11, Page 2028-2039, November 2025.
ABSTRACT Selecting the optimal donor is crucial for optimizing results of allogeneic hematopoietic cell transplantation (allo‐HCT). We analyzed outcomes based on donor type in 2809 myelofibrosis (MF) patients undergoing first allo‐HCT between 2015 and 2021 at EBMT centers.
Juan Carlos Hernández‐Boluda   +24 more
wiley   +1 more source

Pegylated Interferon Alfa-2a for Polycythemia Vera or Essential Thrombocythemia Resistant or Intolerant to Hydroxyurea.

open access: yesBlood, 2019
Prior studies have reported high response rates with recombinant interferon-α (rIFN-α) therapy in patients with essential thrombocythemia (ET) and polycythemia vera (PV).
A. Yacoub   +33 more
semanticscholar   +1 more source

The Essential Thrombocythemia, Thrombotic Risk Stratification, and Cardiovascular Risk Factors

open access: yesAdvances in Hematology, 2020
Essential thrombocythemia is a rare hematological malignancy with good overall survival, but moderate to high risk of developing arterial or venous thrombosis lifelong.
S. Mancuso   +9 more
semanticscholar   +1 more source

Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk‐stratification and management

open access: yesAmerican journal of hematology/oncology, 2018
Disease Overview: Polycythemia vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly, thrombosis, bleeding,
A. Tefferi, T. Barbui
semanticscholar   +1 more source

Triple-Negativity Identifies a Subgroup of Patients with Better Overall Survival in Essential Thrombocythemia

open access: yesHematology Reports, 2022
Essential thrombocythemia, as defined by the WHO in 2016, is a Philadelphia-negative chronic myeloproliferative neoplasm showing a better prognosis than polycythemia vera and myelofibrosis.
Marco Santoro   +7 more
doaj   +1 more source

Emerging treatments for essential thrombocythemia

open access: yesJournal of Blood Medicine, 2011
Steven Okoli, Claire HarrisonDepartment of Haematology, Guy's and St Thomas' NHS Foundation Trust, Great Maze Pond, London, UKAbstract: In 1934, Epstein and Goedel used the term hemorrhagic thrombocythemia to describe a disorder ...
Okoli S, Harrison C
doaj  

AP2M1 Is a Candidate Gene for Microcephaly and Intellectual Disability in 3q27.1 Deletions

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Deletions of the 3q26.33q27.2 region appear to correlate with a distinct phenotype, although there are few reported cases. Here, we present seven previously unreported individuals carrying de novo 3q27 deletions (under 5 Mb), which include the AP2M1 (adaptor‐related protein complex 2, mu‐1 subunit) gene and summarize data from 12 previously ...
Russell Gear   +16 more
wiley   +1 more source

Associations between gender, disease features and symptom burden in patients with myeloproliferative neoplasms: an analysis by the MPN QOL International Working Group

open access: yesHaematologica, 2017
The myeloproliferative neoplasms, including polycythemia vera, essential thrombocythemia and myelofibrosis, are distinguished by their debilitating symptom profiles, life-threatening complications and profound impact on quality of life.
Holly L. Geyer   +51 more
doaj   +1 more source

A Case of Myeloproliferative Neoplasm‐Associated Glomerulopathy in a Patient With Myelofibrosis

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Myeloproliferative neoplasm (MPN)‐related glomerulopathy is a rare, late complication of MPN. Mesangial matrix expansion seems to be the histopathological hallmark. Proteinuria may not always be present. Further exploration is warranted to determine whether risk factors—including disease entity, mutation status and treatment regimens ...
Saskia Leibowitz   +4 more
wiley   +1 more source

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