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Essential Tremor

Medical Clinics of North America, 2019
Essential tremor is one of the most common movement disorders. It is characterized by a bilateral action tremor of the upper limbs. It may be accompanied by tremor of the head, voice, or lower limbs. Essential tremor is often present for years or decades before presentation and it progresses insidiously.
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Essential tremor.

BMJ clinical evidence, 2002
Essential tremor is one of the most common movement disorders throughout the world, with prevalence in the general population of 0.4-3.9%. Although most people with essential tremor are only mildly affected, those who seek medical care are disabled to some extent, and most are socially handicapped by the tremor.We conducted a systematic review and ...
Cristina, Sampaio, Joaquim, Ferreira
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Pathology in essential tremor

Parkinsonism & Related Disorders, 2012
The pathology of essential tremor (ET) is increasingly being studied. The main findings include a reduction in cerebellar Purkinje cells, other pathological changes of cerebellar degeneration and restricted Lewy bodies in the locus ceruleus. This paper will review those findings and put them into context with clinical studies in ET and findings in ...
Holly A. Shill   +2 more
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Nadolol in essential tremor [PDF]

open access: possibleNeurology, 1983
Nadolol, 120 and 240 mg daily, reduced essential tremor in a placebo-controlled double-blind study. The effect was observed in patients who had previously responded to propranolol but not in those who had not benefited from propranolol therapy.
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Genetics of essential tremor

Parkinsonism & Related Disorders, 2012
Essential tremor (ET) is a prevalent condition manifesting with progressive action tremor. Although ET was traditionally viewed as a sporadic disease, a significant proportion of cases report a positive family history of tremor. Autosomal dominant inheritance can be demonstrated in many families.
Barbara Jasinska-Myga, Christian Wider
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Handedness and Essential Tremor

Archives of Neurology, 1985
In patients with essential tremor, a direct relationship was found between hand dominance and severity of hand tremor. A higher incidence of left-handedness was found in patients with essential tremor than in controls.
William C. Koller, Nabil Biary
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‘Orthostatic tremor’ in familial‐essential tremor

Neurology, 1986
We studied a family with essential tremor of the arms. Some members also had tremor of the trunk and legs on standing, but not on walking, sitting, or reclining. Tremor was evoked, regardless of body or limb position, by strong tonic contraction of the appropriate muscles; it was a type of static postural tremor.
Robert D. Currier   +2 more
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The Bereitschaftspotential in essential tremor

Clinical Neurophysiology, 2010
Essential tremor (ET) is an involuntary postural oscillation. It is unclear to which extent motor cortical activity in preparation of volitional movement is abnormal in ET. We measured the Bereitschaftspotential (BP) to address this question.Given the known influence of the cerebello-dentato-thalamo-cortical projection in the generation of the BP ...
Ming-Kuei Lu   +7 more
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Flunarizine in Essential Tremor

Clinical Neuropharmacology, 1993
We studied the effects of flunarizine (Fz) in 10 patients with moderate to severe essential tremor. Tremor was evaluated after 6 weeks of treatment using patient and physician assessment as well as blinded video analysis. Only one patient had mild subjective transient improvement and three experienced worsening of tremor.
Anthony E. Lang, Terry Curran
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Phenobarbitone in essential tremor

Neurology, 1985
We conducted a double-blind, placebo-controlled trial of phenobarbitone on a fixed-dose regimen in 12 patients with essential tremor. The drug was better than placebo on accelerometric measurement and clinical assessment, but not according to patient self-assessment or measures of manual performance.
Lynn Cleeves, Leslie J. Findley
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