Results 41 to 50 of about 3,729,755 (297)

Updates in essential tremor.

Parkinsonism & Related Disorders
Essential tremor (ET) is one of the most common tremor disorders and can be disabling in its affect on daily activities. There have been major breakthroughs in the treatment of tremor and ET is the subject of important ongoing research.
Tyler Okelberry, Kelly E. Lyons, R. Pahwa   +2 more
semanticscholar   +1 more source

Safety and Efficacy of Staged, Bilateral Focused Ultrasound Thalamotomy in Essential Tremor

JAMA Neurology
Key Points Question Is staged, bilateral magnetic resonance–guided focused ultrasound thalamotomy safe and effective for patients with essential tremor?
M. Kaplitt, Vibhor Krishna, Howard M. Eisenberg, W. Elias, P. Ghanouni, Gordon H. Baltuch, A. Rezai, Casey H. Halpern, B. Dalm, P. Fishman, Vivek P. Buch, S. Moosa, H. Sarva, A. Murray   +13 more
semanticscholar   +1 more source

Longitudinal follow-up with VIM thalamic deep brain stimulation for dystonic or essential tremor

Neurology, 2020
Objective To assess longitudinal tremor outcomes with ventral intermediate nucleus deep brain stimulation (VIM DBS) in patients with dystonic tremor (DT) and to compare with DBS outcomes in essential tremor (ET).
T. Tsuboi, Zakia Jabarkheel, Pamela R. Zeilman, M. Barabas, K. Foote, M. Okun, A. Wagle Shukla   +6 more
semanticscholar   +1 more source

Essential tremor: clinical observations

Arquivos de Neuro-Psiquiatria, 1993
The authors have studied 53 patients with essential tremor, focusing its clinical and epidemiological aspects. There were familial history in 37.70% of all cases, prevailing in females (56.60%) and white people (69.80%); nevertheless this difference can ...
João S. Pereira, Maria Lúcia V. Pimentel, Denise H. Nicaretta   +2 more
doaj   +1 more source

Essential Tremor and Depression [PDF]

Movement Disorders Clinical Practice, 2017
AbstractIntroductionDepression and neuropsychiatric disorders in individuals with essential tremor (ET) are not well characterized in the literature.MethodsWe compared 104 ET subjects with 481 non‐ET controls involved in the Arizona Study of Aging and Neurodegenerative Disorders. An analysis of baseline depression scales and neuropsychiatric inventory (
Sana, Aslam, Nan, Zhang, Charles H, Adler, John N, Caviness, Erika, Driver-Dunckley, Shyamal H, Mehta, Marwan N, Sabbagh, Christine, Belden, Edward, Zamrini, Thomas G, Beach, Holly A, Shill   +10 more
openaire   +2 more sources

Pregabalin for essential tremor [PDF]

Cochrane Database of Systematic Reviews, 2012
Essential tremor is one of the most common movement disorders. Treatment primarily consists of pharmacological agents. While primidone and propranolol are well-established treatments in clinical practice, they may be ineffective in 25% to 55% of patients and can produce serious adverse events in a large percentage of them.
Bruno E, NICOLETTI, Alessandra, Quattrocchi G, Filippini G, Colosimo C, ZAPPIA, MARIO   +5 more
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Prospective Home-use Study on Non-invasive Neuromodulation Therapy for Essential Tremor

Tremor and Other Hyperkinetic Movements, 2020
Highlights This prospective study is one of the largest clinical trials in essential tremor to date. Study findings suggest that individualized non-invasive neuromodulation therapy used repeatedly at home over three months results in safe and effective ...
S. Isaacson, E. Peckham, W. Tse, Olga Waln, Christopher Way, Melita Petrossian, N. Dahodwala, M. Soileau, M. Lew, Cameron Dietiker, Nijee S Luthra, P. Agarwal, Rohit Dhall, J. Morgan, N. Calakos, T. Zesiewicz, E. Shamim, R. Kumar, P. LeWitt, H. Shill, A. Simmons, F. Pagán, Pravin Khemani, Jessica Tate, B. Maddux, Lan Luo, W. Ondo, M. Hallett, A. Rajagopal, Paula Chidester, K. Rosenbluth, S. Delp, R. Pahwa   +32 more
semanticscholar   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Alprazolam for essential tremor

Cochrane Database of Systematic Reviews, 2012
Essential tremor (ET) is one of the most common movement disorders. Treatment is based primarily on pharmacological agents. On this basis, although primidone and propranolol are well-established treatments in clinical practice, they could be ineffective in 25% to 55% of patients and can produce serious adverse events (AEs) in a large percentage of ...
Bruno E, NICOLETTI, Alessandra, Quattrocchi G, Filippini G, ZAPPIA, MARIO, Colosimo C.   +5 more
openaire   +4 more sources