Results 201 to 210 of about 1,309,287 (265)

Isothiocyanate-Rich Essential Oil of <i>Morisonia flexuosa</i> L. Exhibits Anxiolytic-like Effects That May Involve Serotonergic Pathways in Zebrafish. [PDF]

Plants (Basel)
Rodrigues FFG, Carvalho NKG, Souza GGO, Santos HSD, de Menezes IRA, Barros Alves AM, Menezes JESA, Rodrigues FFG, Costa JGMD.   +8 more
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Large language models for generating longitudinal synthetic data in low-risk pregnancy care. [PDF]

Data Brief
Pinto G, Crista V, Silva R, Costa B, Bernardi FA, Almeida R, Souza J, Freitas A, Marreiros G, Conceição L.   +9 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

From legacy systems to real-time response: VPD-SMART implementation and its impact on public health surveillance in Paraguay and the Americas.

SSM Health Syst
Ortiz C, Millacura FA, Atavillos C, Bravo-Alcántara P, Espinoza J, Osorio V, Baeza C, Ojeda P, Revilla F, Pacis C, Bobadilla S, Araceli F, Del Medico P, Tejo C, Rossi E, Ordoñez F, Zapata-Bedoya S, Cain E, Tavera P, Magarinos M, Whittembury A, Jean-Baptiste A, Broome K, Ovelar P, Perez T, García M, Villalobos N, Potter R, Cousirat L, Rey-Benito G, Velandia-Gonzalez M.   +30 more
europepmc   +1 more source

A systematic review of machine learning algorithms for mortality risk, readmission and phenotype prediction in patients with heart failure: exploring key data sources, input variables and outcomes. [PDF]

BMC Med Inform Decis Mak
Flok A, Kajüter Rodrigues P, Pohurskyy S, Teuteberg F.   +3 more
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Estimating daily ozone levels in urban ambient air. [PDF]

Environ Monit Assess
Galán-Madruga D, Cárdenas-Escudero J, Broomandi P, Urraca JL, Cáceres JO.   +4 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source