Results 171 to 180 of about 1,374,959 (315)

Inter situ collections as a strategy to conserve an exceptional plant species from the Amazon rainforest. [PDF]

PLoS One
Escobar DFE, Gastauer M, Ramos SJ, Caldeira CF.   +3 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Breaking into the establishment

, 2016
In the 1960s Frederick Wiseman began a series of documentaries exploring institutions – schools, hospitals, government departments and even the Juvenile Court. For him, the institution was the star and a gauge for the health of our society. Nowadays, the
Holden, Karina, Hart, Phoebe, Dorziac, Theo, Hetherton, Madeleine, Cross, Mark, Morris, Shellie   +5 more
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Earnings of Men and Women in Firms with a Female Dominated Workforce: What Drives the Impact of Sex Segregation on Wages? [PDF]

This study analyzes the relationship between the segregation of women across establishments and the salaries paid to men and women. My aim is to separate the impact the proportion of women working within an establishment has upon individual wages.
Heinze, Anja
core  

Ecological opportunity and the onset of polyploid niche expansion waves. [PDF]

Proc Natl Acad Sci U S A
Kauai F, Van de Peer Y, Bonte D.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

On the Connection Between Signcryption and One-pass Key Establishment ∗

, 2007
There is an intuitive connection between signcryption and one-pass key establishment. Although this has been observed previously, up to now there has been no formal analysis of this relationship.
In Galbraith, M. Choudary Gorantla, Gonzàlez Nieto, Juan Manuel, Colin Boyd, The Ima, Key Establishment   +6 more
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Genetic variation in seed dormancy, soil tolerance, and pH response jointly shape early establishment in Lupinus species. [PDF]

Sci Rep
Pesqueira AM, González AM, Gallardo M, Santalla M.   +3 more
europepmc   +1 more source