Results 91 to 100 of about 60,161,579 (305)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Estado del Arte de la Acreditación en Salud en Colombia

, 2021
ilustraciones, gráficos, tablas ; 28 cm.La revisión bibliográfica y de diferentes contenidos, nos propone un acercamiento al conocimiento de aspectos relacionados con el estado del arte de la acreditación en salud en Colombia, las implicaciones del ...
De la Cruz Mallana, Jesús Antonio, Oñate Zambrano, María Mercedes   +1 more
core  

Estado del bienestar y salud pública, una relación que debe ser actualizada

Gaceta Sanitaria, 2018
La salud de las personas ha mejorado a lo largo del siglo xx, al mismo tiempo que se consolidaba el Estado del bienestar. Este trabajo explora la relación actual del Estado del bienestar y la salud pública. Las funciones esenciales de la salud pública se
Fernando G. Benavides, Jordi Delclós, Consol Serra   +2 more
doaj   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source

Percepción del estado de salud y factores asociados en adultos mayores [PDF]

, 2015
Objetivo Analizar los factores sociodemográficos y servicios de salud asociados a la percepción del estado de salud en adultos mayores dela Sociedad San Vicente de Paúl de Medellín en el segundo semestre del año 2011.Materiales y Métodos Estudio ...
Cardona Arango, Doris, Castaño Vergara, Diana Marcela   +1 more
core  

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Situación de las condiciones esenciales para la atención de enfermedades no transmisibles en el Chaco boliviano

Revista Panamericana de Salud Pública
En el marco de una iniciativa regional para fortalecer la atención de enfermedades no transmisibles (ENT) en territorios en situación de vulnerabilidad, se desarrolló y aplicó un módulo específico de la herramienta de valoración de condiciones esenciales
Hector Ojeda-Casares, Roberta de Betânia Caixeta, Noelia Villalta Coro, Armando Medina Ramirez, Dolores Ondarsuhu, Silvana Luciani, Guadalupe Gonzales, Alma Morales Salinas   +7 more
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Caracterización del Estado de Salud Mental de los Estudiantes y de los Programas de Prevención de las Universidades de la RSDUE

, 2023
El presente informe es resultado del proceso de diagnóstico y caracterización, acorde con el primer objetivo de la mesa de salud mental, este es: Caracterización validada del estado de los estudiantes y de los programas de prevención en salud mental de ...
Molina, Macarena, Campos, Roberto, Salinas, Antonio, Bravo Bahamóndez, Felipe, Carvajal, Alonso, Härtel, Steffen   +5 more
core