Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya +10 more
wiley +1 more source
[Scientific output of the Revista Médica del IMSS in PubMed (2005-2025): a bibliometric analysis]. [PDF]
Chávez-Martínez O +2 more
europepmc +1 more source
Arterial Blood‐Mediated Deep‐Tissue Photoacoustic Oximetry
The arterial prior method (APM+) for photoacoustic oximetry is introduced, which leverages the high arterial blood oxygenation to calibrate the fluence at the artery and estimate the oxygenation of the surrounding tissue, thus circumventing the spectral coloring problem. APM+’s accuracy and consistency are shown in a series of phantom and in vivo human
Karteekeya Sastry +7 more
wiley +1 more source
[Response to the Letter to the Editor "The double burden of working women: Gender inequality, the right to health and labour justice"]. [PDF]
García-Rodríguez I +3 more
europepmc +1 more source
Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford +3 more
wiley +1 more source
[The Royal Philanthropic Vaccine Expedition: interview with Susana Ramírez Martín]. [PDF]
Martín SMR +3 more
europepmc +1 more source
A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance
Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng +12 more
wiley +1 more source
Avoidable mortality in childhood in Colombia: A type of violence [PDF]
Hoyos-Quintero ÁM +2 more
europepmc +1 more source
Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton +13 more
wiley +1 more source
Association between neonatal conditions and anthropometric indicators among children attending daycare centers in Southern Brazil. [PDF]
Lourenção LFP +4 more
europepmc +1 more source

