Results 151 to 160 of about 1,252,227 (269)

Compound heterozygous SLC12A5 variants expand the molecular and functional spectrum of KCC2‐developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Overview of the multimodal experimental approach integrating clinical, genetic, in silico, and in vitro investigations. Clinical: Representative EEG recording setup and ictal traces from affected patients. Genetic: Pedigrees for Families A and B highlighting the inheritance of the four identified SLC12A5 variants (A1, A2, B1, B2).
Mira Hamze, Robyn Whitney, Dorothée Ville, Nathalie Villeneuve, Anna‐Maria Hartmann, Lisa Becker, Jens Hausmann, Jinwei Zhang, Cathy Brier, Lucie I. Pisella, Perrine Friedel, Audrey Labalme, Eudeline Alix, Nicolas Chatron, Damien Sanlaville, Sylvie Gory‐Fauré, Eric Denarier, Christophe Porcher, Gaetan Lesca, Igor Medina   +19 more
wiley   +1 more source

Integrated molecular and metatranscriptomic evidence of Tacaribe virus and the brain virome profile of <i>Molossus molossus</i> bat sampled in Brazil. [PDF]

Microbiol Spectr
de Sousa LLF, Sanz Duro RL, de Oliveira Vaz R, de Athayde CL, Martins JO, de Lima Slobosk BSS, Guilardi MD, Cabral-Miranda G, de Oliveira-Filho EF, Drexler JF, Ramos Janini LM, Durães-Carvalho R.   +11 more
europepmc   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, EarlyView.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

Cephalochromin Effects in Triple-Negative Breast Cancer Cells: Apoptosis Induction and Modulation of Survival Pathways. [PDF]

J Nat Prod
Diccini I, Parducci NS, de Almeida BO, Farinella V, Dos Santos PC, de Miranda LBL, Botelho SM, Lima K, Carlos JAEG, Garnique ADMB, Pena Ferreira MJ, Costa-Lotufo LV, Machado-Neto JA.   +12 more
europepmc   +1 more source

A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation

Food Chemistry International, EarlyView.
Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee, Tien‐Fen Kuo, Chun‐Yen Yang, Greta Yang, Wen‐Chin Yang   +4 more
wiley   +1 more source

Ecotoxicological Assessment and Biodegradation of Prednisone by Aquatic Microorganisms. [PDF]

Int J Environ Res Public Health
Miranda ÉM, Cardoso PVR, Moreira CPS, Mol MPG.   +3 more
europepmc   +1 more source

Donkwa Enriched With Goron‐Tula (Azanza garckeana) Modulates Sexual Behavior and Activity of Enzymes Linked With Erectile Dysfunction in High‐Fat Diets/ Streptozotocin‐Induced (STZ/HFD) Diabetic Rats

Food Chemistry International, EarlyView.
(A) Mount number, (B) mount latency, (C) intromission number, and (D) intromission latency are the parameters of sexual behavior. Met = metformin. D100 = 100 Donkwa. D90G10 = 90% Donkwa + 10% Goron‐Tula. D85G15 = 85% Donkwa + 15% Goron‐Tula. D80G20 = 80% Donkwa + 20% Goron‐Tula. The mean ± standard error of the mean (SEM) expressed the results. *Values
O. T. Mamukuyomi, O. S. Ijarotimi, A. A. Badejo   +2 more
wiley   +1 more source

Fecal virome of paraguayan hairy dwarf porcupine (Coendou spinosus, Cuvier, 1823) in Rio de Janeiro, Brazil. [PDF]

Braz J Microbiol
Dos Santos Miranda T, Cosentino MAC, Moreira FRR, Schiffler FB, Coimbra A, Mouta R, Medeiros G, Girardi DL, Wanderkoke V, Lima M, de Oliveira TH, Francisco TM, Soffiati FL, Ferreira SS, Ruiz-Miranda CR, Soares MA, D'arc M, Dos Santos AFA.   +17 more
europepmc   +1 more source

Legacy effects of redlining on the distribution of greenspaces in US cities

Frontiers in Ecology and the Environment, EarlyView.
We investigated how a discriminatory housing policy—redlining—has shaped the spatial patterns and configurations of greenspaces throughout 177 cities in the contiguous US. Housing segregation has been a long‐term development practice that has sequestered communities of color to areas with elevated environmental and public health risks.
Travis Gallo, Mason Fidino, Christopher J Schell, Marccus D Hendricks, Seth B Magle   +4 more
wiley   +1 more source

An effective DNA extraction protocol optimized for tropical swamp peat samples. [PDF]

Microbiol Spectr
Gontijo JB, Valverde Firmino G, Mandro JA, Miranda Reis AL, Bieluczyk W, Feitosa Fernandes JC, Barbosa de Camargo P, Mazza Rodrigues JL, Mui Tsai S, Vidal-Torrado P.   +9 more
europepmc   +1 more source