Results 51 to 60 of about 1,021,196 (293)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Portaria de Credenciamento ENFAM n. 233 de 20 de agosto de 2015 [PDF]
, 2015 Credencia o curso "O Novo Código de Processo Civil" promovido pela Escola da Magistratura do Estado do Rio de ...
Escola Nacional de Formação e Aperfeiçoamento de Magistrados (Brasil) (ENFAM)
core +4 more sources
Estado Novo: "República corporativa"
Revista de História das Ideias, 2006 Res_por:Ao contrario do Fascismo italiano, o sistema politico portugues chamado "Estado Novo", projectado e construido por Oliveira Salazar, com a colaboracao de uma elite de formacao e tendencias politicas diversas, numa logica de convergencia, de "terceira via", social e nacionalista, foi uma Republica.
openaire +1 more source
English-Language Books Censored during Wartime in Estado Novo Portugal [PDF]
, 2017 . In contrast to press censorship, books published in Estado Novo Portugal were not subject to a priori censorship, but rather post-publication censorship.
Gombár, Zsófia
core +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Revista da Faculdade de Letras. Série de História, 2019 The establishment of the Republic, on 5 October 1910, established the figure of the President of the Republic as the Head of the Nation and the main political figure of the country.
Ana Sofía Matos Ferreirao
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source