Results 51 to 60 of about 6,674,734 (293)
Imaginários turísticos no Estado Novo português
PASOS Revista de Turismo y Patrimonio Cultural, 2015 Em 1940, António Ferro disse a um grupo de profissionais de turismo, que visitavam o Gabinete Oficial de Propaganda, que Portugal era uma exposição impressionante do turismo nacional.
Cândida Cadavez
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Revista Espacialidades, 2018 Este artigo tem por objetivo discutir a respeito do conceito de biodemocracia desenvolvido por Cassiano Ricardo na obra Marcha para Oeste: A influência da “Bandeira” na formação social e política do Brasil. É nesta obra que o autor formula suas ideias a respeito da existência de uma democracia racial tipicamente brasileira, pautada pela convivência ...
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Um novo papel para o Estado nas relações internacionais [PDF]
, 2017 O presente artigo analisa o novo papel do Estado nas Relações Internacionais em comparação com o tradicional Estado Westfaliano.O presente artigo analisa o novo papel do Estado nas Relações Internacionais em comparação com o tradicional Estado ...
ARRAES, VIRGILIO
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RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Globalização, direitos sociais e poder local [PDF]
, 2000 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências JurídicasAnálise do processo de globalização econômica neoliberal e o seu impacto perante as instituições da modernidade, principalmente no que tange ao Estado-Nação ...
Santin, Janaína Rigo
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