Results 61 to 70 of about 7,306 (261)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Apnea obstructiva del sueño. Hora de ser tomado en serio por los anestesiólogos

Revista Cubana de Anestesiología y Reanimación, 2009
Introducción: El mantenimiento de la permeabilidad de las vías aéreas superiores es una preocupación compartida por los anestesiólogos y por los médicos involucrados con los disturbios del sueño.
Ariel Gómez Hernández, Roberto Bello Frías, Noris Quintana Santos   +2 more
doaj   +2 more sources

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Artificial Intelligence–Based Online Symptom Assessment Tools for Systemic Lupus Erythematosus Diagnosis: Patient Perspectives

Arthritis Care &Research, EarlyView.
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein, Jennifer L. F. Lee, Evelyne Vinet, Arielle Mendel, Christian A. Pineau, Fares Kalache, Louis‐Pierre Grenier, Sasha Bernatsky   +7 more
wiley   +1 more source

Dinheiro e música popular: uma comparação entre Brasil e Estados Unidos [PDF]

Horizontes Antropológicos, 2016
Resumo A primeira metade do século XX foi um período marcado por uma intensa construção de identidades nacionais no Brasil e nos Estados Unidos. A música popular desses dois países, especialmente o samba e os blues, reflete esses processos. Um dos temas centrais nas canções da época é o dinheiro e o modo como ele permeia o cotidiano.
openaire   +4 more sources

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

The Promotion of Graduate Programs through Clustering Prospective Students

International Journal of Interactive Multimedia and Artificial Intelligence, 2019
The promotion of academic programs, particularly at graduate levels, emerges as a response to market changes. In general, graduate programs are not a first order necessity which makes necessary the right promotion of such programs guarantee the ...
Rosa María Cantón Croda, Damián Emilio Gibaja Romero, Fernando Rey Castillo Villar   +2 more
doaj   +1 more source

Light‐Assisted 3D Printing Techniques and Photocrosslinking Strategies: Recent Advances in Musculoskeletal Tissue Engineering

Advanced Engineering Materials, EarlyView.
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley   +1 more source

De lo tradicional a un nuevo enfoque de microempresas: Modelo conceptual de alianzas estratégicas

Acta Universitaria, 2019
Los nuevos mercados internacionales y nacionales han incrementado la competencia y afectado a lasmicroempresas mexicanas, ya que se enfrentan cada vez más a entornos cambiantes y complejos, los cuales les impiden la permanencia en el mercado.
Consuelo Mora Castellanos, Patricia Cano Olivos, José Luis Martínez Flores, Diana Sánchez-Partida   +3 more
doaj   +1 more source