microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan +4 more
wiley +1 more source
, 1884 Dados retirados da capa.Reunião do Conselho de Estado do Império em resposta ao Aviso Reservado de 17 de junho de 1884 que continha um questionario referente ao elemento servil no Brasil.
Brasil. Conselho de Estado
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Cancer Expenditures and Mortality Trends in Brazil: An Ecological Population-Level Time-Series Analysis, 2008-2023. [PDF]
Cancer MedFonseca LS +4 more
europepmc +1 more source
Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li +17 more
wiley +1 more source
Regional Efficiency, Innovation and Productivity
, 2010 A blossoming stream of the regional innovation systems (RIS) literature is being devoted to investigate the relationship between RIS efficiency and productivity growth.
Bosco, Maria Giovanna
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Downregulation of TRMT9B and its association with clinicopathological features in thyroid cancer: an analysis of public datasets. [PDF]
Einstein (Sao Paulo)Souza IB +7 more
europepmc +1 more source
The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta +11 more
wiley +1 more source
<i>NR3C1</i> Exon 1F Promoter Methylation and mRNA Expression in the Dorsolateral Prefrontal Cortex of Individuals Who Died by Suicide: A Post-Mortem Case-Control Study from Northern Mexico. [PDF]
Brain SciAmador-Segovia YM +9 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Biallelic FIG4 variants classically cause distinct conditions characterized by peripheral neuropathy (Charcot‐Marie‐Tooth disease type 4J) or skeletal dysplasia (Yunis‐Varón syndrome). However, central nervous system involvement is increasingly recognized. The prevalence and specific characteristics of movement disorders within FIG4‐
Andrea Gangfuß +22 more
wiley +1 more source
Community and Regional Planning Self-Study Report
, 2010 Community and Regional Planning Self-Study ...
Community and Regional Planning
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