Results 101 to 110 of about 48,696 (263)

Vulnerabilidad. Reducto o frontera del Estado social

Revista de Derecho Público
El concepto de vulnerabilidad es utilizado cada vez con más frecuencia en el ordenamiento jurídico interno e internacional tanto en normas de Derecho público, como de Derecho privado. A pesar de su auge y naturalización", lo cierto es que es un concepto
Alba Nogueira López
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

DO ESTADO SOCIAL AO ESTADO REGULADOR

, 2013
O modelo de Estado evolui juntamente com a sociedade. As relações sociais tornam-se cada vez mais complexas e o Estado precisa adaptar-se à estas novas conjunturas. A redefinição do papel do Estado passa, necessariamente, pela formação do Estado Regulador, o modelo de Estado Social demonstra-se insustentável e cede espaço à participação da iniciativa ...
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Constitución, norma y ley penal

Revista Jurídica Mario Alario D'filippo, 2015
Este artículo es resultado de un proyecto de investigación cuyo objetivo principal consiste en estudiar los límites, aproximaciones y diferencias entre los conceptos de norma y ley desde una perspectiva ontológica, para comprender su desarrollo ...
Álvaro Salgado González
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Estado democrático y social de derecho.

Boletín Mexicano de Derecho Comparado, 2000
  ESTADO DEMOCRÁTICO Y SOCIAL DE DERECHO Sergio GARCÍA RAMÍREZ ¿Existe un solo Estado democrático y social de derecho? Si no lo hay, ¿cuáles son los tipos admisibles, sin caer en la dispersión, la dilusión del concepto, que a fuerza de decir muchas cosas acabe por no decir ninguna?
openaire   +4 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source