Results 131 to 140 of about 3,120,300 (310)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Constitución, norma y ley penal

open access: yesRevista Jurídica Mario Alario D'filippo, 2015
Este artículo es resultado de un proyecto de investigación cuyo objetivo principal consiste en estudiar los límites, aproximaciones y diferencias entre los conceptos de norma y ley desde una perspectiva ontológica, para comprender su desarrollo ...
Álvaro Salgado González
doaj  

Fundamentos del estado de bienestar: La reforma social (1843 – 1919) [PDF]

open access: yes, 2017
El libro, sobre el que giró la conferencia impartida, fue escrito de manera específica pensando en los estudiantes del Grado de Trabajo social y para cargar de contenido una competencia que estaba en el Libro Blanco para la elaboración de los nuevos ...
Lacalzada Mateo, María José
core  

DO ESTADO SOCIAL AO ESTADO REGULADOR

open access: yes, 2013
O modelo de Estado evolui juntamente com a sociedade. As relações sociais tornam-se cada vez mais complexas e o Estado precisa adaptar-se à estas novas conjunturas. A redefinição do papel do Estado passa, necessariamente, pela formação do Estado Regulador, o modelo de Estado Social demonstra-se insustentável e cede espaço à participação da iniciativa ...
openaire   +1 more source

A base social do Estado penal

open access: yesCrítica Penal y Poder, 2017
A partir de uma interpretação de luta de classes – estado penal como forma neoliberal de controlar o precariato – Loïc Wacquant evoluiu para uma teoria antropológica do estado: estado com uma mão direita penal e uma mão esquerda socio-educativa. Revendo as críticas ao modo como as teorias sociais têm entendido (mal) o que é a sociedade, ao ler
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Examen de la política de vivienda en Euskadi: situación actual y perspectivas

open access: yesRevista Vasca de Administración Pública, 2007
This article tries to frame the current Basque model on housing, the historic path of the European Union and Spain in the field of public policies on housing and therefore it reflects on the context of their inception, being always conscious of their ...
Javier Burón Cuadrado
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Estado social y privatizaciones.

open access: yesCuadernos de Relaciones Laborales, 1998
Sin ...
openaire   +2 more sources

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