Results 241 to 250 of about 4,882,386 (282)

The transcriptional dynamics of TIFY/JAZ and BBX families in jasmonate signaling reveal SlBBX17 as a positive regulator of tomato defense. [PDF]

Plant Cell Rep
Lira BS, Barbosa LG, Campos ML, Moreira J, Ponciano G, Wu RTA, Shiose L, Ntelkis N, de Setta N, Goossens A, Freschi L, Rossi M.   +11 more
europepmc   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

The many dimeric faces of Lys49 PLA₂-like proteins: Conformational plasticity and membrane binding drive functional dimer states. [PDF]

Protein Sci
Lima DCA, Dos Santos VF, Rassi B, Ward RJ, Soares TA.   +4 more
europepmc   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

Ectopic Gallstone Presenting As Small Bowel Obstruction: A Diagnostic Challenge. [PDF]

Cureus
Trinidad Cruz DH, Jasso Rodriguez HS, Zermeño JM, Coello Uribe GJ.   +3 more
europepmc   +1 more source

Global identification of Chromobacterium violaceum T6SS effectors reveals an Rhs antibacterial toxin featuring FIX and ADP-ribosyltransferase domains. [PDF]

J Biol Chem
Alves JA, Pankov G, Frey AM, Trost M, Sgro GG, Coulthurst SJ, da Silva Neto JF.   +6 more
europepmc   +1 more source

Efficacy and safety of sacubitril/valsartan in patients on peritoneal dialysis: a systematic review and meta-analysis. [PDF]

J Bras Nefrol
Silva CLD, Fonseca PEO, Calice-Silva V, Ponce D, Rocha PN, Guimarães MG.   +5 more
europepmc   +1 more source

A Hanks-type bacterial kinase, PknS, directly phosphorylates the alternative sigma factor EcfK to promote resistance to protist predation. [PDF]

FEBS J
Lima LDP, Sriranganadane D, da Silva DL, Drebes Dörr NC, Mello EBS, Dos Reis CV, Lourenço RF, Santos JFTDS, Salmazo A, Miranda BW, Massirer KB, Couñago RM, Alvarez-Martinez CE.   +12 more
europepmc   +1 more source

Practical Guide and Best Practices for Diffusion NMR Processing With GNAT. [PDF]

Magn Reson Chem
Cabral TLG, Dal Poggetto G, Tormena CF, Nilsson M.   +3 more
europepmc   +1 more source

A Leaf-Expressed <i>TERMINAL FLOWER1</i> Homolog from Coffee with Alternative Splice Forms Alters Flowering and Branching in Arabidopsis. [PDF]

Plants (Basel)
Cardon CH, Lesy V, Fust C, Ribeiro THC, Hebb O, de Oliveira RR, Minow MAA, Rume GC, Chalfun-Junior A, Colasanti J.   +9 more
europepmc   +1 more source