[Technological and market analysis of the hemodialysis membranes segment in Brazil based on federal public procurement data]. [PDF]
Barcelos GFJ +3 more
europepmc +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
[Trans fatty acids in nutrition labeling and ingredient listing of prepackaged products in Costa Rica, 2022Ácidos graxos <i>trans</i> na rotulagem nutricional e na lista de ingredientes de produtos pré-embalados na Costa Rica, 2022]. [PDF]
Núñez-Rivas HP +6 more
europepmc +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
[Expansion of access to specialized care: the experience of Regional Health Consortia in Bahia, Brazil]. [PDF]
Souza LEPF +7 more
europepmc +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Health policies in Brazil (2016-2022): neoliberalism, pandemic, and threats to the Brazilian Unified National Health System. [PDF]
Machado CV, Lima LD.
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
The COVID-19 pandemic and access to vaccines in Latin America and the Caribbean: strategies adopted by the WHO and PAHOPandemia de COVID-19 e acesso a vacinas na América Latina e Caribe: estratégias da OMS e da OPAS. [PDF]
Bermudez L, Machado CV.
europepmc +1 more source

