Results 61 to 70 of about 277,381 (319)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Unusual facet and co-catalyst effects in TiO2-based photocatalytic coupling of methane

open access: yesNature Communications
Photocatalytic coupling of methane to ethane and ethylene (C2 compounds) offers a promising approach to utilizing the abundant methane resource. However, the state-of-the-art photocatalysts usually suffer from very limited C2 formation rates.
Huizhen Zhang   +11 more
doaj   +1 more source

Study of the influence of fermentation conditions on the content of aroma-forming substances in young red wines

open access: yesНовые технологии, 2023
One of the main requirements for young wines is preservation the qualities of the grapes, including the bright varietal aroma characteristic of essential oils concentrated in the grape skins.
L. V. Gnetko   +3 more
doaj   +1 more source

An ionic liquid catalyzed probase method for one-pot synthesis of alpha,beta-unsaturated esters from esters and aldehydes under mild conditions

open access: yes, 2017
A one-pot synthesis of alpha,beta-unsaturated esters from unactivated esters and aldehydes using strong bases, such as sodium alkoxide and potassium tert-butoxide, was reported.
Li, Zengxi   +9 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Effect of catalytic conditions on the synthesis of new aconitate esters [PDF]

open access: yes, 2011
Sugar cane is a crop which generates large amounts of biomass and a juice rich in highvalue natural molecules. After extracting sugar from the juice, the recovering of various compounds such as organic acids contained in molasses could contribute to ...
Lacaze-Dufaure, Corinne   +10 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

The mesomorphic phase transition temperatures of the unsymmetrical 1,4-phenylene esters of the 4-n-alkoxybenzoic acids [PDF]

open access: yes, 1971
The normal melting process occurs at a specific temperature, characteristic of every substance, when the constituent molecules of the solid have sufficient vibrational kinetic energy to overcome the net attractive forces binding the crystal lattice.
Haut, Stephen A.   +1 more
core  

One-pot esterification and amidation of phenolic acids

open access: yes, 2014
We developed a new one-pot reaction of phenolic acids to afford the corresponding esters and amides through acyl-protected and activated phenolic acid intermediates.
Nakamura, Kozo   +9 more
core   +1 more source

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