DNA Virus Detection in Olfactory Neuroblastomas Using Targeted Enrichment NGS. [PDF]
ABSTRACT A variety of malignancies can be found in the sinonasal tract including the nasal cavity, paranasal sinuses, and skull base. Many of these are attributed to viruses, for example, carcinomas with the presence of transcriptionally active high‐risk human papillomavirus, as well as Epstein–Barr virus associated malignant lymphoepithelial carcinoma
Jauhiainen MK +7 more
europepmc +2 more sources
Does Hyams Grade Impact Outcomes in Olfactory Neuroblastoma? [PDF]
The Laryngoscope, Volume 135, Issue 12, Page 4485-4486, December 2025.
Patel EA +4 more
europepmc +2 more sources
Cancer Stem Cell Characterization in Olfactory Neuroblastoma Tissue. [PDF]
Key Points Cancer stem cells are uncommon in olfactory neuroblastoma When present, cancer stem cells are more likely to be PD‐L1 ...
Ramolia S +9 more
europepmc +2 more sources
Enhancing Diagnostic Accuracy in Sinonasal Neuroendocrine Tumors: The Case for DOTATATE PET Over FDG PET. [PDF]
ABSTRACT Neuroendocrine tumors (NET) are a heterogeneous group of neoplasms that arise from neuroendocrine cells and commonly originate in the GI tract, lungs, and pancreas, but can also present in the skull base and paranasal sinuses. While fluorodeoxyglucose positron emission tomography (FDG PET) scans are routinely used in the evaluation of ...
Sabbaj M +12 more
europepmc +2 more sources
Esthesioneuroblastoma Presenting with Bilateral Proptosis and Blindness in a Child: A Case Report [PDF]
Esthesioneuroblastoma is a rare malignant tumour of the olfactory epithelium. The most common symptom is related to unilateral nasal obstruction. It rarely presents with bilateral proptosis and blindness.
Mahdi Shahriari +2 more
doaj +1 more source
Extent of Resection and Role of Adjuvant Radiotherapy in Olfactory Neuroblastoma Without Definite Radiologic Evidence of Dural Invasion. [PDF]
ABSTRACT Objectives To evaluate the impact of the extent of resection and adjuvant radiotherapy (RT) on treatment outcomes in patients with early‐stage olfactory neuroblastoma (ONB) without definite dural invasion. Methods A retrospective review of ONB cases from two centers within a single institution between 1992 and 2023 was performed ...
Won TB +8 more
europepmc +2 more sources
The Endoscopic Versus Open Approach for Anterior Skull Base Tumors: A Systematic Review of Comparative Outcomes and a Framework for Surgical Selection. [PDF]
Background Anterior skull base tumors (ASBTs) pose significant surgical challenges due to their proximity to critical neurovascular structures. Surgical management has evolved with the adoption of both endoscopic and open approaches. This systematic review synthesizes evidence comparing these approaches in terms of complications, outcomes, and ...
Mian UU +8 more
europepmc +2 more sources
Image findings of cranial nerve pathology on [18F]-2- deoxy-D-glucose (FDG) positron emission tomography with computerized tomography (PET/CT): a pictorial essay. [PDF]
This article aims to increase awareness about the utility of (18)F -FDG-PET/CT in the evaluation of cranial nerve (CN) pathology. We discuss the clinical implication of detecting perineural tumor spread, emphasize the primary and secondary (18)F -FDG-PET/
Muzaffar, Razi +3 more
core +3 more sources
Case Report: Esthesioneuroblastoma Involving the Optic Pathways
Olfactory neuroblastoma, or esthesioneuroblastoma, is an uncommon malignant tumor originating from the neural crest that commonly occurs in the upper nasal cavity.
Vithor Ely B. da Silva +5 more
doaj +1 more source
Hyams Grade and Ki-67 as Predictive Factors for Primary Treatment Failure in Olfactory Neuroblastoma. [PDF]
The aim of the present study was to investigate the influence of various prognostic parameters on the occurrence of primary tumor progression and/or tumor recurrence (TPR) in esthesioneuroblastoma after primary curative therapy in a single center. Time to first TPR in esthesioneuroblastoma was significantly shorter in cases with a younger age and ...
Koch M +5 more
europepmc +2 more sources

