Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Association analysis of seven candidate genes with performance traits in Czech Large White pigs
Czech Journal of Animal Science, 2011 In this study association analyses were performed between genes tagged SNP (IGF2, NAMPT, DGAT1, MYF4, MC3R, MC4R and MYOD1), performance traits (backfat thickness, lean meat content, average daily gain from birth to the end of the test, average daily ...
F. Weisz +3 more
doaj +1 more source
A genomic estimated breeding value-assisted reduction method of single nucleotide polymorphism sets: a novel approach for determining the cutoff thresholds in genome-wide association studies and best linear unbiased prediction. [PDF]
Anim Cells Syst (Seoul), 2023 Lee YS, Oh JD, Lee JY, Shin D.
europepmc +1 more source
Development of a Next-Generation NIL Library in Arabidopsis Thaliana for Dissecting Complex Traits [PDF]
, 2013 The identification of the loci and specific alleles underlying variation in quantitative traits is an important goal for evolutionary biologists and breeders.
Bauerle, William L. +8 more
core +3 more sources
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
AnimalsBovine progressive ataxia in Charolais cattle was first described in the 1970s; then, cases were reported in Charolais worldwide. A homozygous loss-of-function mutation within the KIF1C gene (c.608G>A) was found to be responsible for this ...
Felix Manuel Bischofberger +2 more
doaj +1 more source
Genomic Estimated Breeding Value of Milk Performance and Fertility Traits in the Russian Black-and-White Cattle Population. [PDF]
Acta Naturae, 2022 Sharko FS, Khatib A, Prokhortchouk EB.
europepmc +1 more source
Associations between the K232A polymorphism in the diacylglycerol-O-transferase 1 (DGAT1) gene and performance in Irish Holstein-Friesian dairy cattle [PDF]
, 2010 peer-reviewedSelection based on genetic polymorphisms requires accurate quantification of the effect or association of the polymorphisms with all traits of economic importance. The objective of this study was to estimate, using progeny performance data
Berry, Donagh +5 more
core
Environmental Correlations in Pedigree Estimates of Breeding Value
Journal of Dairy Science, 1970 Abstract Effects of environmental correlations among the records of ancestors of bulls in artificial breeding were evaluated with data from the Holstein-Friesian Association of America. Formulas developed for the variances and covariances of means of records and progeny group means included the effects of distribution of records in both herds and ...
G.M. Thomson, A.E. Freeman
openaire +1 more source