RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
LH supplementation in ovarian stimulation: propensity score and generalized estimating equations analysis over 2000 embryos. [PDF]
Front Endocrinol (Lausanne)Dizdar M +8 more
europepmc +1 more source
An extension of Peskun ordering to continuous time Markov chains [PDF]
Peskun ordering is a partial ordering defined on the space of transition matrices of discrete time Markov chains. If the Markov chains are reversible with respect to a common stationary distribution "greek Pi", Peskun ordering implies an ordering on the ...
Leisen Fabrizio, Mira Antonietta
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han +8 more
wiley +1 more source
Network generalized estimating equations for complexly correlated data with applications to cluster randomized trials. [PDF]
BiostatisticsChen T, Li F, Wang R.
europepmc +1 more source
Comparison of Three Glomerular Filtration Rate Estimating Equations with 24-Hour Urine Creatinine Clearance Measurement in Potential Living Kidney Donors. [PDF]
Int J Nephrol, 2023 Giron-Luque F +3 more
europepmc +1 more source
Rank estimating equations for random effects models
In this paper, we propose an R-estimate for random effects in two stages: given the random effects, rank estimating equations for the regression parameters are constructed, estimates for random effects and variance parameters are then updated until the ...
Chen, Chu-chih
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
Dynamic prediction model for early postoperative pain based on generalized estimating equations: a multi-timepoint longitudinal study. [PDF]
Am J Transl ResLiao Y, Li N, Chen J, Tang Z.
europepmc +1 more source
The psychological impact of the COVID-19 pandemic in the elderly in southwest China: A longitudinal study based on generalized estimating equations. [PDF]
Int J Disaster Risk Reduct, 2023 Wang Y, Luo B, Wang J, Liao S.
europepmc +1 more source