Results 141 to 150 of about 2,375,094 (333)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Standard Error Estimation in Invariance Alignment

open access: yesMathematics
The invariance alignment (IA) method enables group comparisons in factor models involving either continuous or discrete items. This article evaluates the performance of the commonly used delta method for standard error estimation against alternative ...
Alexander Robitzsch
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

A weighted error-minimizer parameter estimation technique for one-inflated positive Poisson distribution

open access: yesResults in Control and Optimization
An error-minimizing estimator is always preferred in model fittings. However, each error-minimizing estimator minimizes error differently. This paper combines four error-minimizing estimators, which are root mean-squared error, mean absolute error, root ...
Razik Ridzuan Mohd Tajuddin
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Uncertainty estimation with prediction-error circuits

open access: yesNature Communications
Neural circuits continuously integrate noisy sensory stimuli with predictions that often do not perfectly match, requiring the brain to combine these conflicting feedforward and feedback inputs according to their uncertainties.
Loreen Hertäg   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy