Results 101 to 110 of about 168,974 (306)

Anti‐CD20 Discontinuation Versus Continuation in People Aged Over 50 With Non‐Active Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether discontinuing anti‐CD20 therapy in people with relapsing‐onset MS aged over 50 is associated with an increased risk of relapse, inflammatory activity, confirmed disability accrual, and serious infection compared with continuing therapy.
Alexia Moukhine, Fabien Rollot, Romain Casey, Nicolas Collongues, Sandra Vukusic, Guillaume Mathey, Anne Laure Dubessy, Jonathan Ciron, Jérôme De Seze, Aurélie Ruet, Pierre Labauge, Arnaud Kwiatkowski, Hélène Zephir, Caroline Papeix, Gilles Defer, Christine Lebrun‐Frenay, David Axel Laplaud, Eric Berger, Eric Thouvenot, Jean Pelletier, Abdullatif Al Khedr, Olivier Casez, Bertrand Bourre, Abir Wahab, Laurent Magy, Jean‐Philippe Camdessanché, Ines Doghri, Solène Moulin, Mariana Sarov Rivière, Karolina Hankiewicz, Amélie Dos Santos, Corinne Pottier, Eric Manchon, Jennifer Aboab, Maia Tchikviladze, Thomas David, Gilles Edan, Emmanuelle Le Page, Laure Michel, Anne Kerbrat, OFSEP Investigators   +40 more
wiley   +1 more source

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato, Alessia Giugno, Miriam Sturniolo, Enrico Fratto, Pio Zoleo, Francesca Felicia Operto, Ilaria Sammarra, Antonio Gambardella   +7 more
wiley   +1 more source

A Step Forward in Post-Mortem Interval Estimation: Multivariate Analysis of Ammonium, Albumin, and Potassium Levels in Vitreous Humor

Diagnostics
Background/Objectives: Accurate post-mortem interval (PMI) estimation remains challenging in forensic pathology. Although potassium (K+) is the most well-validated single biomarker in vitreous humor (VH), multivariate approaches may enhance precision by ...
Martina Focardi, Beatrice Defraia, Ilenia Bianchi, Barbara Gualco, Andrea Costantino, Rossella Grifoni, Alessandra Fanelli, Tiziana Biagioli, Costanza Bossi, Vilma Pinchi, Luisa Lanzilao   +10 more
doaj   +1 more source

The multivariate Bernoulli detector: change point estimation in discrete survival analysis

Biometrics
Abstract Time-to-event data are often recorded on a discrete scale with multiple, competing risks as potential causes for the event. In this context, application of continuous survival analysis methods with a single risk suffers from biased estimation.
Willem van den Boom, Maria De Iorio, Fang Qian, Alessandra Guglielmi   +3 more
openaire   +4 more sources

Addressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus

Arthritis Care &Research, EarlyView.
Objective Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined the following: (1) associations between economic insecurities and PROs, and (2) the impact of screening and addressing economic ...
Jay Patel, Tripti Singh, Meredith Ingersoll, Shelby Gomez, Amanda Weber, Sarah E. Panzer, Sancia Ferguson, Christie M. Bartels, Shivani Garg   +8 more
wiley   +1 more source

The effect of training distribution, duration, and volume on VO2max and performance in trained cyclists: A systematic review, multilevel meta-analysis, and multivariate meta-regression.

Journal of Science and Medicine in Sport
OBJECTIVE This study aimed to systematically investigate whether polarized or non-polarized training leads to greater physiological and performance adaptations in cyclists.
Ben Cove, S. Chalmers, H. Bennett, Max Nelson, M. Anderson   +4 more
semanticscholar   +1 more source

Rank estimation and the multivariate analysis of in vivo fast-scan cyclic voltammetric data

Analytical Chemistry, 2010
Principal component regression has been used in the past to separate current contributions from different neuromodulators measured with in vivo fast-scan cyclic voltammetry. Traditionally, a percent cumulative variance approach has been used to determine
Richard B Keithley, Regina M. Carelli, R. Wightman   +2 more
semanticscholar   +1 more source

Multivariate analysis of the volumetric capnograph for PaCO2 estimation.

International journal of burns and trauma, 2015
End-tidal CO2 (eTCO2) can be used to estimate the arterial CO2 (PaCO2) under steady-state conditions, but that relationship deteriorates during hemodynamic or respiratory instability. We developed a multivariate method to improve our ability to estimate the PaCO2, by using additional information contained in the volumetric capnograph (Vcap) waveform ...
Slava M, Belenkiy, William L, Baker, Andriy I, Batchinsky, Sumit, Mittal, Taylor, Watkins, Jose, Salinas, Leopoldo C, Cancio   +6 more
openaire   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Reliability Estimation of Reciprocating Seals Based on Multivariate Dependence Analysis and Its Experimental Validation

IEEE Access, 2019
Accurate reliability estimation for reciprocating seals is of great significance due to their wide use in numerous engineering applications. This work proposes a reliability estimation method for reciprocating seals based on multivariate dependence ...
Chao Zhang, Rentong Chen, Shaoping Wang, Yujie Qian, Mileta M. Tomovic   +4 more
doaj   +1 more source