Results 151 to 160 of about 59,165 (246)

Polygenic risk score and prostate specific antigen predict death from prostate cancer in men with intermediate aggressive cancer

International Journal of Cancer, EarlyView.
What's New? Using 21 SNPs, two novel PRS were constructed and used to develop two new machine‐learning classifiers, one for the detection of prostate cancer and the other for the prediction of its aggressiveness and subsequent mortality. The classifier for disease detection is built using the PRS as the sole feature, whereas the one for disease ...
Leandro Rodrigues Santiago, Efthymios Ladoukakis, Dorota Scibior‐Bentkowska, Belinda Nedjai   +3 more
wiley   +1 more source

Real‐world efficacy and toxicity of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma according to IMDC risk criteria—A multi‐center retrospective analysis on behalf of the GUARDIANS group

International Journal of Cancer, EarlyView.
What's New? The combination of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma has demonstrated durable response and tolerability in clinical trials. However, inclusion criteria for clinical studies are restrictive, and patients in the real‐world setting tend to have more comorbidities.
Hendrik Dinkel, Linus Materna, Ramona Stelmach, Stefanie Zschäbitz, Stephanie Neuberger, Can D. Aydogdu, Jozefina Casuscelli, Timo Egenolf, Matteo Silberg, Julie Steinestel, Arne Strauss, Florian Kirchhoff, Marit Ahrens, Pia Paffenholz, Richard Cathomas, Berna C. Özdemir, Christopher Gossler, Philipp Ivanyi, Marc Rehlinghaus, Thomas Hilser, Viktor Grünwald, Katrin Schlack   +21 more
wiley   +1 more source

Considerations for Estimating Causal Effects of Informatively Timed Treatments. [PDF]

Epidemiology
Oganisian A.
europepmc   +1 more source

Characteristics and overall survival in patients with T1 melanoma: A nationwide matched cohort study

International Journal of Cancer, EarlyView.
What's New? Thin cutaneous malignant melanoma has an excellent ten‐year melanoma‐specific survival of 93%–97%. Moreover, the incidence of melanoma is higher among individuals with high socioeconomic status, which may protect them from other diseases. This nationwide matched cohort study found that patients with thin cutaneous malignant melanoma have a ...
Ylva Naeser, Rasmus Mikiver, Karolin Isaksson, Mats Lambe, Gustav J. Ullenhag   +4 more
wiley   +1 more source

Modelling dependent censoring in time-to-event data using boosting copula regression. [PDF]

Lifetime Data Anal
Strömer A, Klein N, Van Keilegom I, Mayr A.   +3 more
europepmc   +1 more source

Efficacy and safety of fruquintinib combined with albumin‐bound paclitaxel as second‐line therapy for advanced gastric cancer following failure of PD‐1 inhibitor‐containing treatment (TACTIC GC‐01): A phase II single‐arm study

International Journal of Cancer, EarlyView.
What's New? Anti‐angiogenic drugs have shown promising efficacy as a second‐line treatment for advanced gastric cancer. However, it remains unclear how alterations in the tumor microenvironment following first‐line immunotherapy may impact tumor angiogenesis and influence subsequent therapeutic outcomes. This single‐arm study prospectively explored the
Xiaoting Ma, Kai Ou, Xiu Liu, Biyang Cao, Wenwei Yang, Jingyu Lu, Letian Zhang, Qi Wang, Lizhen Gao, Zhichao Jiang, Yongkun Sun, Lin Yang   +11 more
wiley   +1 more source

Analysis of the time to breast cancer diagnosis in Cuba: an observational study. [PDF]

BMC Public Health
Koley T.
europepmc   +1 more source

Changes in 1‐year relative survival of patients with cancer during the COVID‐19 pandemic in Denmark, Finland, Iceland, Norway, and Sweden: A population‐based cohort study

International Journal of Cancer, EarlyView.
What's New? In the first year of the COVID‐19 pandemic, cancer reporting in the Nordic countries declined, presumably owing to delays in cancer diagnosis. How the pandemic impacted cancer survival in these countries, however, remains unclear. Using data from Nordic cancer registries that together include more than 27 million people, the authors of the ...
Fernando Gonzalez Yli‐Mäyry, Tomas Tanskanen, Karri Seppä, Anna L. V. Johansson, Charlotte Wessel Skovlund, Lina Steinrud Mørch, Søren Friis, Simon Mathis Kønig, Tom Børge Johannesen, Tor Åge Myklebust, Sasha Pejicic, David Pettersson, Eva María Guðmundsdóttir, Sirpa Heinävaara, Nea Malila, Joonas Miettinen, Johan Ahlgren, Giske Ursin, Janne Pitkäniemi   +18 more
wiley   +1 more source

Advancing censored geochemical Au prediction through Bayesian spatial models and Random Forest with fractal-based background separation. [PDF]

Sci Rep
Mahdiyanfar H.
europepmc   +1 more source

Cumulative exposure to tacrolimus is associated with increased risk of malignancy for solid organ transplant recipients

International Journal of Cancer, EarlyView.
What's New? Long‐term immunosuppression in solid organ transplant recipients (SOTRs) is linked to increased cancer risk. Although this risk potentially increases with greater immunosuppressant exposure, the exact dose‐response pattern remains uncertain.
Sergio A. Acuna, Xun Zhao, Maggie Jones‐Carr, Graham Smith, Kyla Naylor, Bima J. Hasjim, Shiyi Chen, An‐Wen Chan, Nancy Baxter, S. Joseph Kim, Mamatha Bhat   +10 more
wiley   +1 more source